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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Proteins
Interactions
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Reactions
Reach

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Organisms
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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

15,701–15,750 of 31,435, by identifier

quercetin 3,3'-bissulfate + 3'-phosphoadenylyl sulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalancedRhea 21860
an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)
Left to rightBalance undeterminableRhea 21864
2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O + H(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)
Direction not assertedBalancedRhea 21868
(6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + NADH + 2 H(+)
Direction not assertedBalancedRhea 21876
oxalate + O2 + 2 H(+) = H2O2 + 2 CO2
Direction not assertedBalancedRhea 21880
trithionate + H2O = thiosulfate + sulfate + H(+)
Direction not assertedBalancedRhea 21884

(1S,2S)-OPC-8 + NADP(+) = (9S,13S,15Z)-12-oxophyto-10,15-dienoate + NADPH + H(+)

Direction not assertedBalancedRhea 21888

D-arabinose + NADP(+) = D-arabinono-1,4-lactone + NADPH + H(+)

Direction not assertedBalancedRhea 21892

(R)-1-aminopropan-2-yl phosphate + adenosylcob(III)yrate + ATP = adenosylcob(III)inamide phosphate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 21896

scytalone + NADP(+) = naphthalene-1,3,6,8-tetrol + NADPH + H(+)

Direction not assertedBalancedRhea 21908

pyruvate + CoA + O2 + H(+) = acetyl-CoA + H2O2 + CO2

Direction not assertedBalancedRhea 21912

2 Fe(III)-[cytochrome c550] + an aliphatic amine + H2O = 2 Fe(II)-[cytochrome c550] + an aldehyde + NH4(+) + 2 H(+)

Direction not assertedBalance undeterminableRhea 21916

UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate = Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UMP

Direction not assertedBalancedRhea 21920

3-dehydro-L-gulonate + NAD(+) = 2,3-dioxo-L-gulonate + NADH + H(+)

Direction not assertedBalancedRhea 21924

3-dehydro-L-gulonate + NADP(+) = 2,3-dioxo-L-gulonate + NADPH + H(+)

Direction not assertedBalancedRhea 21928

S-adenosyl-L-methionine = L-homoserine lactone + S-methyl-5'-thioadenosine

Direction not assertedBalancedRhea 21932

carbamoyl phosphate + putrescine = N-carbamoylputrescine + phosphate + H(+)

Direction not assertedBalancedRhea 21936

D-cellobiose + ATP = 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + ADP + H(+)

Direction not assertedBalancedRhea 21944

formamide + H2O = formate + NH4(+)

Direction not assertedBalancedRhea 21948

5alpha-pregnane-3,20-dione + NADP(+) = progesterone + NADPH + H(+)

Right to leftBalancedRhea 21952

vitexin + UDP-alpha-D-glucose = vitexin 2''-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 21956

an acylcholine + H2O = a carboxylate + choline + H(+)

Direction not assertedBalance undeterminableRhea 21964

7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate

Direction not assertedBalancedRhea 21968

precorrin-1 + S-adenosyl-L-methionine = precorrin-2 + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 21972

[thioredoxin]-disulfide + sulfite + AMP + 2 H(+) = adenosine 5'-phosphosulfate + [thioredoxin]-dithiol

Direction not assertedBalance undeterminableRhea 21976

alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = N-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalance undeterminableRhea 21980

choline + 3'-phosphoadenylyl sulfate = choline sulfate + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 21984

pelargonidin 3-O-(6-O-[(E)-caffeoyl]-beta-D-glucoside) 5-O-beta-D-glucoside + malonyl-CoA = 4'''-demalonylsalvianin + CoA

Direction not assertedBalancedRhea 21988

L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)

Left to rightBalance undeterminableRhea 21992

a 1-O-alkyl-2-acetyl-sn-glycerol + an acyl-CoA = a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA

Direction not assertedBalance undeterminableRhea 21996

D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)

Direction not assertedBalancedRhea 22000

L-seryl-[myosin light chain] + ATP = O-phospho-L-seryl-[myosin light chain] + ADP + H(+)

Left to rightBalance undeterminableRhea 22004

L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA

Direction not assertedBalancedRhea 22008

precorrin-4 + S-adenosyl-L-methionine = precorrin-5 + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 22012

[glutaredoxin]-dithiol + arsenate + glutathione + H(+) = glutathionyl-S-S-[glutaredoxin] + arsenite + H2O

Direction not assertedBalance undeterminableRhea 22016

molybdate(out) + ATP + H2O = molybdate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 22020

trimethylamine + NAD(+) + H2O = trimethylamine N-oxide + NADH + 2 H(+)

Direction not assertedBalancedRhea 22024

taxa-4(20),11-dien-5alpha-ol + acetyl-CoA = taxa-4(20),11-dien-5alpha-yl acetate + CoA

Direction not assertedBalancedRhea 22028

3-oxalomalate = oxaloacetate + glyoxylate

Direction not assertedBalancedRhea 22032

[phosphate](n) + D-glucose = [phosphate](n-1) + D-glucose 6-phosphate + H(+)

Direction not assertedBalance undeterminableRhea 22036

N-formyl-L-aspartate + H2O = L-aspartate + formate

Direction not assertedBalancedRhea 22040

K(+)(out) + ATP + H2O + H(+)(in) = K(+)(in) + ADP + phosphate + 2 H(+)(out)

Left to rightBalancedTransportRhea 22044

7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate + H(+)

Direction not assertedBalancedRhea 22048

A + NH4(+) + H2O = hydroxylamine + AH2 + H(+)

Direction not assertedBalancedRhea 22052

hexadecan-1-ol + NAD(+) = hexadecanal + NADH + H(+)

Direction not assertedBalancedRhea 22056

(4R,5S)-dethiobiotin + (sulfur carrier)-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (sulfur carrier)-H + biotin + 2 5'-deoxyadenosine + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]

Direction not assertedBalance undeterminableRhea 22060

5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H2O

Direction not assertedBalancedRhea 22064

(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + NADPH + H(+)

Direction not assertedBalancedRhea 22068

L-ribulose + ATP = L-ribulose 5-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 22072

[protein] with 2 [4Fe-4S] clusters + sulfite + 6 AH2 + 2 S-adenosyl-L-methionine = [protein] with [8Fe-9S-C] cluster + 5'-deoxyadenosine + L-methionine + 6 A + S-adenosyl-L-homocysteine + 3 H2O + 8 H(+)

Direction not assertedBalance undeterminableRhea 22076

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