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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

15,651–15,700 of 31,435, by identifier

CDP-alpha-D-paratose = CDP-3,6-dideoxy-alpha-D-mannose
Direction not assertedBalancedRhea 21656
benzaldehyde + NADP(+) + H2O = benzoate + NADPH + 2 H(+)
Left to rightBalancedRhea 21660
4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate + H(+)
Direction not assertedBalancedRhea 21664
sn-glycerol 3-phosphate(out) + ATP + H2O = sn-glycerol 3-phosphate(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 21668
[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine
Direction not assertedBalance undeterminableRhea 21672
2 dimethylallyl diphosphate = (R)-lavandulyl diphosphate + diphosphate
Direction not assertedBalancedRhea 21676

(2S)-2-hydroxyphytanate + O2 = 2-oxophytanate + H2O2

Direction not assertedBalancedRhea 21680

(R)-beta-alanopine + NAD(+) + H2O = beta-alanine + pyruvate + NADH + H(+)

Direction not assertedBalancedRhea 21684

a polyvinyl alcohol + n O2 = an oxidized polyvinyl alcohol + n H2O2

Direction not assertedBalance undeterminableRhea 21688

CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H(+)

Direction not assertedBalancedRhea 21692

N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 21696

5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate

Direction not assertedBalancedRhea 21700

L-tyrosine + H2O = phenol + pyruvate + NH4(+)

Direction not assertedBalancedRhea 21704

S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine

Left to rightBalancedRhea 21708

L-threo-3-phenylserine = benzaldehyde + glycine

Left to rightBalancedRhea 21712

(S)-mandelate + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + O2 = (S)-4-hydroxymandelate + (6R)-L-erythro-6,7-dihydrobiopterin + H2O

Direction not assertedBalancedRhea 21716

formamide = hydrogen cyanide + H2O

Direction not assertedBalancedRhea 21720

a nitrile + 2 H2O = a carboxylate + NH4(+)

Direction not assertedBalance undeterminableRhea 21724

GDP-alpha-D-mannose + 2 NAD(+) + H2O = GDP-alpha-D-mannuronate + 2 NADH + 3 H(+)

Direction not assertedBalancedRhea 21728

chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate + H(+)

Direction not assertedBalancedRhea 21732

(3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate

Direction not assertedBalancedRhea 21736

2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H(+)

Direction not assertedBalance undeterminableRhea 21740

S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H(+)

Direction not assertedBalancedRhea 21744

(S)-lactaldehyde + NADP(+) = methylglyoxal + NADPH + H(+)

Direction not assertedBalancedRhea 21748

all-trans-violaxanthin = all-trans-capsorubin

Direction not assertedBalancedRhea 21752

deacetylisoipecoside + H2O = secologanin + dopamine

Direction not assertedBalancedRhea 21756

(3S)-3-hydroxybutanoyl-CoA = (3R)-3-hydroxybutanoyl-CoA

Direction not assertedBalancedRhea 21760

heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+)

Left to rightBalance undeterminableRhea 21764

N-methyl-L-alanine + NADP(+) + H2O = methylamine + pyruvate + NADPH + H(+)

Direction not assertedBalancedRhea 21768

cytidine(6666) in apoB mRNA + H2O + H(+) = uridine(6666) in apoB mRNA + NH4(+)

Left to rightBalancedRhea 21772

(25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate + ATP + CoA = (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 21776

cyclohexanone + A = cyclohex-2-enone + AH2

Direction not assertedBalancedRhea 21780

N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2-oxoglutarate + O2 = N(6)-methyl-L-lysyl(36)-[histone H3] + formaldehyde + succinate + CO2

Left to rightBalance undeterminableRhea 21788

propan-2-ol + NADP(+) = acetone + NADPH + H(+)

Direction not assertedBalancedRhea 21792

dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + NADPH + H(+)

Direction not assertedBalancedRhea 21796

all-trans-antheraxanthin + L-ascorbate = all-trans-zeaxanthin + L-dehydroascorbate + H2O

Direction not assertedBalancedRhea 21800

myo-inositol + ATP = 1D-myo-inositol 3-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 21804

2,5-dioxopiperazine + H2O = glycylglycine

Direction not assertedBalancedRhea 21808

cholesterol + reduced [NADPH--hemoprotein reductase] + O2 = 7alpha-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 21812

a D-alpha-amino acid + O2 + H2O = a 2-oxocarboxylate + H2O2 + NH4(+)

Left to rightBalance undeterminableRhea 21816

L-homocysteine + S-adenosyl-L-methionine = L-methionine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 21820

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

Left to rightBalancedRhea 21824

nitrite + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = nitrate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)

Direction not assertedBalance undeterminableRhea 21828

3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 21832

D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H2O

Direction not assertedBalancedRhea 21836

N(6),N(6)-dimethyl-L-lysyl-[histone] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 21840

phenylacetyl-CoA + L-glutamine = N(2)-phenylacetyl-L-glutamine + CoA + H(+)

Direction not assertedBalancedRhea 21844

(E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide

Direction not assertedBalancedRhea 21848

(R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O

Direction not assertedBalancedRhea 21852

cyclohexa-1,5-diene-1-carbonyl-CoA + H2O = 6-hydroxycyclohex-1-ene-1-carbonyl-CoA

Direction not assertedBalancedRhea 21856

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