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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

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Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

15,251–15,300 of 31,435, by identifier

hydroxylamine + O2 = nitrite + H2O + H(+)
Direction not assertedBalancedRhea 19969
S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = spermine + S-methyl-5'-thioadenosine + H(+)
Left to rightBalancedRhea 19973
L-tyrosine methyl ester + 3'-phosphoadenylyl sulfate = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalancedRhea 19977
S-(hydroxymethyl)glutathione + NADP(+) = S-formylglutathione + NADPH + H(+)
Direction not assertedBalancedRhea 19981
S-(hydroxymethyl)glutathione + NAD(+) = S-formylglutathione + NADH + H(+)
Direction not assertedBalancedRhea 19985
5-(methylsulfanyl)-alpha-D-ribose 1-phosphate = 5-(methylsulfanyl)-D-ribulose 1-phosphate
Direction not assertedBalancedRhea 19989
[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol

Direction not assertedBalance undeterminableRhea 19993

phosphoenolpyruvate + H2O = pyruvate + phosphate

Direction not assertedBalancedRhea 19997

glycolaldehyde + NAD(+) + H2O = glycolate + NADH + 2 H(+)

Direction not assertedBalancedRhea 20001

an alpha-D-glucuronoside + H2O = D-glucuronate + an alcohol

Direction not assertedBalance undeterminableRhea 20005

2-hydroxy-2-methylpropanenitrile + UDP-alpha-D-glucose = linamarin + UDP + H(+)

Direction not assertedBalancedRhea 20009

carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)

Direction not assertedBalancedRhea 20013

5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 = 5,10-methylenetetrahydromethanopterin + H(+)

Direction not assertedBalancedRhea 20017

deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2

Direction not assertedBalancedRhea 20021

gibberellin A3 + UDP-alpha-D-glucose = gibberellin A3 O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 20025

10-deoxysarpagine + NADP(+) = vellosimine + NADPH + H(+)

Direction not assertedBalancedRhea 20029

isopenicillin N = penicillin N

Direction not assertedBalancedRhea 20033

D-sorbitol 6-phosphate + NADP(+) = aldehydo-D-glucose 6-phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 20037

3-oxopropanoate + NADP(+) + H2O = malonate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 20041

3-oxopropanoate + NAD(+) + H2O = malonate + NADH + 2 H(+)

Direction not assertedBalancedRhea 20045

1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide

Direction not assertedBalancedRhea 20049

ribitol + NAD(+) = D-ribulose + NADH + H(+)

Direction not assertedBalancedRhea 20053

N-carbamoylsarcosine + H2O + 2 H(+) = sarcosine + NH4(+) + CO2

Direction not assertedBalancedRhea 20057

2'-deoxycytidine + a ribonucleoside 5'-triphosphate = dCMP + a ribonucleoside 5'-diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 20061

2'-deoxymugineate + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineate + succinate + CO2 + H(+)

Direction not assertedBalancedRhea 20065

(Z)-phenylacetaldehyde oxime = phenylacetonitrile + H2O

Direction not assertedBalancedRhea 20069

D-allo-threonine = acetaldehyde + glycine

Direction not assertedBalancedRhea 20073

guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 20077

N-methylhexanamide + H2O = hexanoate + methylamine

Direction not assertedBalancedRhea 20081

a flavonol 3-O-beta-D-glucoside + malonyl-CoA = a flavonol 3-O-(6-O-malonyl-beta-D-glucoside) + CoA

Direction not assertedBalance undeterminableRhea 20085

L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H(+)

Direction not assertedBalancedRhea 20089

an anthocyanidin + UDP-alpha-D-glucose + H(+) = an anthocyanidin 3-O-beta-D-glucoside + UDP

Direction not assertedBalance undeterminableRhea 20093

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O

Direction not assertedBalancedRhea 20097

a long-chain fatty acid + L-cysteinyl-[protein] + ATP = an S-(long-chain fatty acyl)-L-cysteinyl-[protein] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 20101

beta-D-fructose 6-phosphate + ADP = beta-D-fructose 1,6-bisphosphate + AMP + H(+)

Direction not assertedBalancedRhea 20105

alpha-D-ribose 1,5-bisphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP

Direction not assertedBalancedRhea 20109

beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate

Direction not assertedBalancedRhea 20113

L-rhamnulose + ATP = L-rhamnulose 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 20117

tRNA(Gln) + L-glutamine + ATP = L-glutaminyl-tRNA(Gln) + AMP + diphosphate

Direction not assertedBalancedRhea 20121

2 reduced [2Fe-2S]-[ferredoxin] + NADP(+) + H(+) = 2 oxidized [2Fe-2S]-[ferredoxin] + NADPH

Direction not assertedBalance undeterminableRhea 20125

AMP + H2O = D-ribose 5-phosphate + adenine

Direction not assertedBalancedRhea 20129

3-(indol-3-yl)lactate + NAD(+) = indole-3-pyruvate + NADH + H(+)

Direction not assertedBalancedRhea 20133

10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA

Direction not assertedBalancedRhea 20137

an S-alkyl-L-cysteine S-oxide = an S-alkyl sulfenate + 2-aminoprop-2-enoate

Direction not assertedBalance undeterminableRhea 20141

quinine + reduced [NADPH--hemoprotein reductase] + O2 = 3-hydroxyquinine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 20149

L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 20153

a polyvinyl alcohol + 2n Fe(III)-[cytochrome c] = an oxidized polyvinyl alcohol + 2n Fe(II)-[cytochrome c] + 2n H(+)

Direction not assertedBalance undeterminableRhea 20157

alpha-D-galactosyl-(1->3)-1D-myo-inositol + sucrose = raffinose + myo-inositol

Direction not assertedBalancedRhea 20161

an N(5)-acyl-L-ornithine ester + H2O = an N(5)-acyl-L-ornithine + an alcohol + H(+)

Direction not assertedBalance undeterminableRhea 20165

pyridoxine + UDP-alpha-D-glucose = 5'-O-beta-D-glucosylpyridoxine + UDP + H(+)

Direction not assertedBalancedRhea 20177

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