Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

15,201–15,250 of 31,435, by identifier

FMN-N(5)-oxide + NADH + H(+) = FMN + NAD(+) + H2O
Direction not assertedBalancedRhea 19761
glycerol = 3-hydroxypropanal + H2O
Direction not assertedBalancedRhea 19765
phaseollidin hydrate = phaseollidin + H2O
Direction not assertedBalancedRhea 19769
sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + NADPH + H(+)
Direction not assertedBalancedRhea 19773
L-pipecolate + A = L-1-piperideine-6-carboxylate + AH2 + H(+)
Direction not assertedBalancedRhea 19777
3,5-diiodo-L-tyrosine + 2-oxoglutarate = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate
Direction not assertedBalancedRhea 19781
dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + H2O

? Direction not asserted

Balanced

Rhea 19785

4-(dimethylamino)azobenzene + NADP(+) + H2O = 4-(dimethylamino)phenylazoxybenzene + NADPH + H(+)

Direction not assertedBalancedRhea 19789

(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + sarcosine + oxidized [electron-transfer flavoprotein] + H(+) = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + reduced [electron-transfer flavoprotein] + glycine

Left to rightBalance undeterminableRhea 19793

1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate

Left to rightBalancedRhea 19797

(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate

Left to rightBalancedRhea 19801

a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate

Direction not assertedBalance undeterminableRhea 19805

(S)-ureidoglycolate + H2O + 2 H(+) = glyoxylate + 2 NH4(+) + CO2

Direction not assertedBalancedRhea 19809

a 2-oxocarboxylate + L-asparagine = 2-oxosuccinamate + an L-alpha-amino acid

Direction not assertedBalance undeterminableRhea 19813

(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADPH + H(+)

Right to leftBalancedRhea 19817

(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADH + H(+)

Direction not assertedBalancedRhea 19821

(2E,6E)-farnesyl diphosphate = (+)-aristolochene + diphosphate

Direction not assertedBalancedRhea 19825

a primary alcohol + O2 = an aldehyde + H2O2

Direction not assertedBalance undeterminableRhea 19829

(6R)-10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+)

Direction not assertedBalancedRhea 19833

D-sorbitol 6-phosphate + NAD(+) = beta-D-fructose 6-phosphate + NADH + H(+)

Direction not assertedBalancedRhea 19837

N-formylmethanofuran + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = methanofuran + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+)

Direction not assertedBalance undeterminableRhea 19841

nocardicin E + S-adenosyl-L-methionine = isonocardicin A + S-methyl-5'-thioadenosine + H(+)

Direction not assertedBalancedRhea 19845

NADP(+) + H2O = ADP-D-ribose 2'-phosphate + nicotinamide + H(+)

Left to rightBalancedRhea 19849

a 16alpha-hydroxysteroid + NADP(+) = a 16-oxosteroid + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 19857

a 16alpha-hydroxysteroid + NAD(+) = a 16-oxosteroid + NADH + H(+)

Direction not assertedBalance undeterminableRhea 19861

uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2

Left to rightBalancedRhea 19865

an acyl-CoA + glycine = an N-acylglycine + CoA + H(+)

Left to rightBalance undeterminableRhea 19869

dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)

Direction not assertedBalancedRhea 19873

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)

Left to rightBalance undeterminableRhea 19877

L-lysyl-[protein] + GTP = N(epsilon)-GMP-L-lysyl-[protein] + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 19881

(S)-reticuline + O2 = (S)-scoulerine + H2O2 + H(+)

Direction not assertedBalancedRhea 19885

alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate

Left to rightBalancedRhea 19889

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP

Direction not assertedBalancedRhea 19893

2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O

Left to rightBalancedRhea 19897

L-tryptophan + O2 = alpha,beta-didehydrotryptophan + H2O2

Direction not assertedBalancedRhea 19901

spermidine + NAD(+) = dehydrospermidine + NADH + H(+)

Direction not assertedBalancedRhea 19905

(S)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)

Direction not assertedBalance undeterminableRhea 19909

a (3R)-hydroxyacyl-[ACP] + NAD(+) = a 3-oxoacyl-[ACP] + NADH + H(+)

Direction not assertedBalance undeterminableRhea 19913

D-ribitol 5-phosphate + NADP(+) = D-ribulose 5-phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 19921

D-ribitol 5-phosphate + NAD(+) = D-ribulose 5-phosphate + NADH + H(+)

Direction not assertedBalancedRhea 19925

[(1->4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-beta-D-glucosyl](n+1) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 19929

alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate

Left to rightBalancedRhea 19933

glycine + S-adenosyl-L-methionine = sarcosine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 19937

norcoclaurine + S-adenosyl-L-methionine = coclaurine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 19941

N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 19945

(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate

Direction not assertedBalancedRhea 19949

a 2-oxocarboxylate + L-alanine = an L-alpha-amino acid + pyruvate

Direction not assertedBalance undeterminableRhea 19953

2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H(+)

Direction not assertedBalancedRhea 19957

a 2'-deoxyribonucleoside + a ribonucleoside 5'-phosphate = a ribonucleoside + a 2'-deoxyribonucleoside 5'-phosphate

Direction not assertedBalance undeterminableRhea 19961

S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+)

Direction not assertedBalancedRhea 19965

Page 305 of 629