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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

15,051–15,100 of 31,435, by identifier

D-glucose 6-sulfate + H2O = sulfate + D-glucose + H(+)
Direction not assertedBalancedRhea 19145
L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+)
Left to rightBalance undeterminableRhea 19149
UDP-alpha-D-apiose + apigenin 7-O-beta-D-glucoside = 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone + UDP + H(+)
Direction not assertedBalancedRhea 19153
D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H2O
Direction not assertedBalancedRhea 19157
a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-[alpha-D-glucosyl-(1-> 2)-alpha-D-glucosyl]-sn-glycerol + UDP + H(+)
Direction not assertedBalance undeterminableRhea 19165
L-serine = pyruvate + NH4(+)
Direction not assertedBalancedRhea 19169

naphthalene + NADH + O2 + H(+) = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+)

Direction not assertedBalancedRhea 19173

L-lysine = (3S)-3,6-diaminohexanoate

Direction not assertedBalancedRhea 19177

a very-long-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a very-long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 19181

propanoyl-CoA + glyoxylate + H2O = 2-hydroxyglutarate + CoA + H(+)

Direction not assertedBalancedRhea 19185

N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2

Left to rightBalance undeterminableRhea 19189

all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH2

Direction not assertedBalancedRhea 19193

adenosine 5'-phosphosulfate + NH4(+) = adenosine 5'-phosphoramidate + sulfate + 2 H(+)

Direction not assertedBalancedRhea 19197

2'-deoxyguanosine + ATP = dGMP + ADP + H(+)

Direction not assertedBalancedRhea 19201

dCTP + 2 H2O = dUMP + NH4(+) + diphosphate

Direction not assertedBalancedRhea 19205

codeine + NADP(+) = codeinone + NADPH + H(+)

Direction not assertedBalancedRhea 19209

an S-substituted L-cysteine + acetyl-CoA = an N-acetyl-L-cysteine-S-conjugate + CoA + H(+)

Left to rightBalance undeterminableRhea 19213

1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+)

Direction not assertedBalancedRhea 19217

2 formaldehyde + H2O = methanol + formate + H(+)

Direction not assertedBalancedRhea 19221

glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine = glycin-2-yl radical-[formate C-acetyltransferase] + semiquinone [flavodoxin] + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalance undeterminableRhea 19225

an aromatic aldehyde + AMP + diphosphate + NADP(+) = an aromatic carboxylate + ATP + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 19229

S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)

Left to rightBalance undeterminableRhea 19233

4-methylmuconolactone = 3-methylmuconolactone

Direction not assertedBalancedRhea 19237

ent-kaur-16-en-19-oate + reduced [NADPH--hemoprotein reductase] + O2 = ent-7alpha-hydroxykaur-16-en-19-oate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 19241

N-phenylhydroxylamine = 2-aminophenol

Direction not assertedBalancedRhea 19245

L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

Direction not assertedBalancedRhea 19249

a sphingomyelin + H2O = phosphocholine + an N-acylsphing-4-enine + H(+)

Left to rightBalance undeterminableRhea 19253

a secondary alcohol + NADP(+) = a ketone + NADPH + H(+)

Right to leftBalance undeterminableRhea 19257

heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 19261

carnitine + NAD(+) = 3-dehydrocarnitine + NADH + H(+)

Direction not assertedBalancedRhea 19265

2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 19269

N-acetyl-D-mannosamine + phosphoenolpyruvate + H2O = N-acetylneuraminate + phosphate

Direction not assertedBalancedRhea 19273

tRNA(Pyl) + L-pyrrolysine + ATP = L-pyrrolysyl-tRNA(Pyl) + AMP + diphosphate

Direction not assertedBalancedRhea 19277

(7S)-marmesin + reduced [NADPH--hemoprotein reductase] + O2 = psoralen + acetone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 19281

a di-trans,poly-cis-dolichol + a 1,2-diacyl-sn-glycero-3-phosphocholine = an acyl-di-trans,poly-cis-dolichol + a 1-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 19285

sucrose 6(F)-phosphate + H2O = sucrose + phosphate

Direction not assertedBalancedRhea 19289

a monoacylglycerol + ATP = a monoacyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalance undeterminableRhea 19293

beta-alanine + L-histidine + ATP = carnosine + ADP + phosphate + H(+)

Left to rightBalancedRhea 19297

histamine + S-adenosyl-L-methionine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 19301

3-hydroxybenzoyl-CoA + 3 malonyl-CoA + 2 H(+) = 2,3',4,6-tetrahydroxybenzophenone + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 19305

2-O-(alpha-D-mannosyl)-3-phosphoglycerate + H2O = (2R)-2-O-(alpha-D-mannosyl)-glycerate + phosphate

Direction not assertedBalancedRhea 19309

an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivative + CMP + H(+)

Left to rightBalance undeterminableRhea 19313

5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + hydrogencarbonate + ATP = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate + 2 H(+)

Direction not assertedBalancedRhea 19317

N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde

Direction not assertedBalancedRhea 19321

quinolin-4-ol + NADH + O2 + H(+) = quinoline-3,4-diol + NAD(+) + H2O

Direction not assertedBalancedRhea 19325

nuatigenin + UDP-alpha-D-glucose = nuatigenin 3-beta-D-glucopyranoside + UDP + H(+)

Direction not assertedBalancedRhea 19329

oxalyl-CoA + H(+) = formyl-CoA + CO2

Direction not assertedBalancedRhea 19333

2 hydroxylamine + 2 NAD(+) = hyponitrous acid + 2 NADH + 2 H(+)

Direction not assertedBalancedRhea 19337

octane + 2 reduced [rubredoxin] + O2 + 2 H(+) = 2 oxidized [rubredoxin] + octan-1-ol + H2O

Direction not assertedBalance undeterminableRhea 19341

(6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate = (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate

Direction not assertedBalancedRhea 19345

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