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1,451–1,500 of 12,877 reactions from Human-GEM
leucine[c] = leucine[m]
ReversibleBalancedTransportEC 1.1.1.28Transport reactionsHuman-GEM MAR01480
CoA[m] + tetracosanoylcarnitine[m] = L-carnitine[m] + tetracosanoyl-CoA[m]
ReversibleBalancedEC 2.3.1.21Fatty acid oxidationHuman-GEM MAR01481
tetracosanoylcarnitine[c] = tetracosanoylcarnitine[m]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR01482
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol[c] + H+[c] + NADPH[c] = 14-demethyllanosterol[c] + NADP+[c]
Left to rightBalancedEC 1.3.1.70Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01484
L-lactate[c] = L-lactate[m]
Left to rightBalancedTransportEC 2.3.1.21Transport reactionsHuman-GEM MAR01485
(6Z,9Z)-octadecadienoylcarnitine[c] = (6Z,9Z)-octadecadienoylcarnitine[m]
ReversibleBalancedTransportEC 4.4.1.5Fatty acid oxidationHuman-GEM MAR01486
linoleic-carnitine[c] = linoleic-carnitine[m]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR01487
L-carnitine[c] + linolenoyl-CoA[c] = CoA[c] + Alpha-Linolenyl Carnitine[c]
ReversibleBalancedEC 2.3.1.21Fatty acid oxidationHuman-GEM MAR01488
CoA[m] + Alpha-Linolenyl Carnitine[m] = L-carnitine[m] + linolenoyl-CoA[m]
ReversibleBalancedEC 2.3.1.21Fatty acid oxidationHuman-GEM MAR01489
14-demethyllanosterol[c] + H+[c] + NADPH[c] + O2[c] = 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.18.9Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01490
Alpha-Linolenyl Carnitine[c] = Alpha-Linolenyl Carnitine[m]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR01491
gamma-linolenoylcarnitine[c] = gamma-linolenoylcarnitine[m]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR01492
4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + H+[c] + NADPH[c] + O2[c] = 4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + 2 H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.18.9Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01493
4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + H+[c] + NADPH[c] + O2[c] = 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.18.9Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01494
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + NADP+[c] = 3-keto-4-methylzymosterol[c] + CO2[c] + H+[c] + NADPH[c]
Left to rightBalancedEC 1.1.1.170Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01495
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + NAD+[c] = 3-keto-4-methylzymosterol[c] + CO2[c] + H+[c] + NADH[c]
Left to rightBalancedEC 1.1.1.170Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01496
2 H+[c] + lanosterol[c] + 3 NADPH[c] + 3 O2[c] = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol[c] + formate[c] + 4 H2O[c] + 3 NADP+[c]
Left to rightBalancedEC 1.14.14.1Cholesterol metabolismHuman-GEM MAR01497
squalene 2,3-oxide[r] = lanosterol[r]
Left to rightBalancedEC 5.4.99.7Cholesterol metabolismHuman-GEM MAR01498
2-lysolecithin pool[e] = 2-lysolecithin pool[c]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR01499
3-keto-4-methylzymosterol[c] + 3 H+[c] + NADP+[c] = 4alpha-methylzymosterol[c] + NADPH[c]
ReversibleUnbalancedEC 1.1.1.270Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01500
PC-LD pool[c] + retinol[c] = 2-lysolecithin pool[c] + retinyl-ester[c]
Left to rightBalance undeterminableEC 2.3.1.135Vitamin A metabolismHuman-GEM MAR01501
4alpha-methylzymosterol[c] + H+[c] + NADPH[c] + O2[c] = 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.18.9Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01502
4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + H+[c] + NADPH[c] + O2[c] = 4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + 2 H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.18.9Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01503
4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol[c] + H+[c] + NADPH[c] + O2[c] = 4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.18.9Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01504
4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol[c] + NADP+[c] = 5alpha-cholesta-8,24-dien-3-one[c] + CO2[c] + H+[c] + NADPH[c]
Left to rightBalancedEC 1.1.1.170Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01505
11-cis-retinol[c] + PC-LD pool[c] = 2-lysolecithin pool[c] + retinyl-ester[c]
Left to rightBalance undeterminableEC 1.14.14.1Vitamin A metabolismHuman-GEM MAR01506
9-cis-retinol[c] + PC-LD pool[c] = 2-lysolecithin pool[c] + fatty acid 9-cis-retinol[c]
Left to rightBalance undeterminableEC 5.4.99.7Vitamin A metabolismHuman-GEM MAR01507
5alpha-cholesta-7,24-dien-3beta-ol[r] + H+[r] + NADPH[r] + O2[r] = 7-dehydrodesmosterol[r] + 2 H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.19.20Cholesterol metabolismHuman-GEM MAR01508
5alpha-cholesta-8,24-dien-3-one[c] + H+[c] + NADPH[c] = NADP+[c] + zymosterol[c]
Left to rightBalancedEC 1.1.1.270Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01509
H+[r] + lathosterol[r] + NADPH[r] + O2[r] = 2 H2O[r] + NADP+[r] + provitamin D3[r]
Left to rightBalancedEC 1.14.19.20Cholesterol metabolismHuman-GEM MAR01510
glycophosphatidylinositol-(GPI)-anchored-protein-precursor[r] + Mannosyl-3-(Phosphoethanolaminyl-Mannosyl)-Glucosaminyl-Acylphosphatidylinositol (M4A))[r] = gpi_sig[r] + Mannosyl-3-(Phosphoethanolaminyl-Mannosyl)-Glucosaminyl-Acylphosphatidylinositol-Protein (M4A)[r]
Left to rightBalance undeterminableEC 1.4.3.14Phosphatidylinositol phosphate metabolismHuman-GEM MAR01511
zymosterol[c] = 5alpha-cholesta-7,24-dien-3beta-ol[c]
Left to rightBalancedEC 5.3.3.5Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01512
mem2emgacpail heparan sulfate[r] + PE-LD pool[r] = 1,2-diacylglycerol-LD-PE pool[r] + Mannosyl-3-(Phosphoethanolaminyl-Mannosyl)-Glucosaminyl-Acylphosphatidylinositol (M4A))[r]
Left to rightBalance undeterminablePhosphatidylinositol phosphate metabolismHuman-GEM MAR01513
1-acylglycerol-3P pool[e] = 1-acylglycerol-3P pool[c]
ReversibleBalance undeterminableTransportEC 1.2.1.5Transport reactionsHuman-GEM MAR01514
5alpha-cholesta-7,24-dien-3beta-ol[c] + H+[c] + NADPH[c] + O2[c] = 7-dehydrodesmosterol[c] + 2 H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.19.20Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01516
[ACP][m] + malonyl-CoA[m] = CoA[m] + malonyl-[ACP][m]
ReversibleBalance undeterminableEC 2.3.1.39Fatty acid oxidationHuman-GEM MAR01517
ATP[c] + H2O[c] + L-metanephrine[c] = ADP[c] + H+[c] + L-metanephrine[e] + Pi[c]
Left to rightBalancedTransportEC 1.1.1.37Transport reactionsHuman-GEM MAR01518
7-dehydrodesmosterol[c] + H+[c] + NADPH[c] = desmosterol[c] + NADP+[c]
Left to rightBalancedEC 1.3.1.21Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01519
(R)-mevalonate[x] + ATP[x] = (R)-5-phosphomevalonate[x] + ADP[x] + H+[x]
Left to rightBalancedEC 2.7.1.36Cholesterol metabolismHuman-GEM MAR01520
H+[c] + methylmalonyl-CoA[c] = CO2[c] + propanoyl-CoA[c]
Left to rightBalancedEC 4.1.1.9Valine, leucine, and isoleucine metabolismHuman-GEM MAR01521
H+[x] + methylmalonyl-CoA[x] = CO2[x] + propanoyl-CoA[x]
Left to rightBalancedEC 4.1.1.9Valine, leucine, and isoleucine metabolismHuman-GEM MAR01522
H2O[m] + N4-acetylaminobutanal[m] + NAD+[m] = 4-acetamidobutanoate[m] + 2 H+[m] + NADH[m]
Left to rightBalancedEC 1.2.1.88Arginine and proline metabolismHuman-GEM MAR01523
H+[l] + Tn-antigen[l] + UDP[l] = UDP-N-acetyl-D-galactosamine[l] + Protein-Linked Serine Or Threonine Residue (O-Glycosylation Site)[l]
Left to rightBalance undeterminableEC 3.2.1.49Keratan sulfate degradationHuman-GEM MAR01524
chloride[c] + H+[c] + HCO3-[e] + Na+[e] = chloride[e] + H+[e] + HCO3-[c] + Na+[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01525
desmosterol[c] + H+[c] + NADPH[c] = cholesterol[c] + NADP+[c]
Left to rightBalancedEC 1.3.1.72Cholesterol biosynthesis 1 (Bloch pathway)Human-GEM MAR01526
Na+[e] = Na+[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01527
Na+[c] + NH4+[e] = Na+[e] + NH4+[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01528
Ca2+[e] + 4 Na+[c] + NH4+[e] = Ca2+[c] + 4 Na+[e] + NH4+[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01529
cholesterol[c] = cholesterol[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01530
H+[c] + NADH[c] + O2[c] + provitamin D3[c] = 27alpha-hydroxy-7-dehydrocholesterol[c] + H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.15.15Cholesterol metabolismHuman-GEM MAR01531