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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

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Anatomy
Cell types
Organisms
Materials
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Diseases

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

14,901–14,950 of 31,435, by identifier

ergosterol + NADP(+) = ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADPH + H(+)
Direction not assertedBalancedRhea 18501
L-lysine + NAD(+) = Delta(1)-piperideine-2-carboxylate + NH4(+) + NADH + H(+)
Direction not assertedBalancedRhea 18505
H2O2 + NADH + H(+) = NAD(+) + 2 H2O
Direction not assertedBalancedRhea 18509
D-mannitol + O2 = D-mannose + H2O2
Direction not assertedBalancedRhea 18513
licodione + S-adenosyl-L-methionine = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 18521
3-methylbutan-1-ol + NADP(+) = 3-methylbutanal + NADPH + H(+)
Direction not assertedBalancedRhea 18525
3-methylbutan-1-ol + NAD(+) = 3-methylbutanal + NADH + H(+)

? Direction not asserted

Balanced

Rhea 18529

5-hydroxy-L-tryptophan + H(+) = serotonin + CO2

Direction not assertedBalancedRhea 18533

salicylaldehyde + NAD(+) + H2O = salicylate + NADH + 2 H(+)

Direction not assertedBalancedRhea 18537

10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine = dihydrochelirubine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 18541

2-dehydro-3-deoxy-L-arabinonate = glycolaldehyde + pyruvate

Direction not assertedBalancedRhea 18545

[(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + UDP + H(+)

Left to rightBalance undeterminableRhea 18549

(2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + NADH + H(+)

Direction not assertedBalancedRhea 18553

a 1-O-alkyl-sn-glycero-3-phosphate + acetyl-CoA = a 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA

Direction not assertedBalance undeterminableRhea 18557

4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H(+)

Direction not assertedBalancedRhea 18561

holo-[lovastatin nonaketide synthase] + 9 malonyl-CoA + S-adenosyl-L-methionine + 11 NADPH + 19 H(+) = dihydromonacolin L-[lovastatin nonaketide synthase] + S-adenosyl-L-homocysteine + 9 CO2 + 11 NADP(+) + 9 CoA + 6 H2O

Direction not assertedBalance undeterminableRhea 18565

an aromatic aldehyde + O2 + H2O = an aromatic carboxylate + H2O2 + H(+)

Direction not assertedBalance undeterminableRhea 18569

dihydrochelirubine + O2 + H(+) = chelirubine + H2O2

Direction not assertedBalancedRhea 18573

3-hydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine = 3-methoxy-5-methyl-1-naphthoate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 18577

ethanolamine + O2 + H2O = glycolaldehyde + H2O2 + NH4(+)

Direction not assertedBalancedRhea 18581

D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate

ReversibleBalancedRhea 18585

[glutamine synthetase]-L-tyrosine + ATP = [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + diphosphate

Direction not assertedBalance undeterminableRhea 18589

sphinganine 1-phosphate = hexadecanal + phosphoethanolamine

Left to rightBalancedRhea 18593

2 reduced [rubredoxin] + NAD(+) + H(+) = 2 oxidized [rubredoxin] + NADH

Direction not assertedBalance undeterminableRhea 18597

3,4-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO2

Direction not assertedBalancedRhea 18601

1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 18605

N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + phosphate + H(+)

Direction not assertedBalancedRhea 18609

4-methoxybenzoate + AH2 + O2 = 4-hydroxybenzoate + formaldehyde + A + H2O

Direction not assertedBalancedRhea 18613

oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2

Direction not assertedBalancedRhea 18617

a (2S)-flavan-4-one + 2-oxoglutarate + O2 = a (2R,3R)-dihydroflavonol + succinate + CO2

Direction not assertedBalance undeterminableRhea 18621

D-galactose + NADP(+) = D-galactono-1,5-lactone + NADPH + H(+)

Direction not assertedBalancedRhea 18625

NAD(+) + ATP = ADP + NADP(+) + H(+)

Direction not assertedBalancedRhea 18629

hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)

Direction not assertedBalancedRhea 18633

H2 + NADP(+) = NADPH + H(+)

Direction not assertedBalancedRhea 18637

H2 + a menaquinone = a menaquinol

Direction not assertedBalance undeterminableRhea 18641

2 putrescine = sym-homospermidine + NH4(+)

Direction not assertedBalancedRhea 18645

D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O

Direction not assertedBalancedRhea 18649

barbiturate + H2O = 3-oxo-3-ureidopropanoate

Direction not assertedBalancedRhea 18653

(R)-glycerate + NADP(+) = 3-hydroxypyruvate + NADPH + H(+)

Direction not assertedBalancedRhea 18657

N(5)-[1(S)-1-carboxyethyl]-L-ornithine + NADP(+) + H2O = L-ornithine + pyruvate + NADPH + H(+)

Direction not assertedBalancedRhea 18661

[phosphate](n) + (2R)-3-phospho-glyceroyl phosphate = [phosphate](n+1) + (2R)-3-phosphoglycerate

Direction not assertedBalance undeterminableRhea 18665

adenosine + H2O = D-ribose + adenine

Direction not assertedBalancedRhea 18669

L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+)

Left to rightBalance undeterminableRhea 18673

phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine + phosphate

Direction not assertedBalancedRhea 18681

pentachlorophenol + NADPH + O2 + H(+) = 2,3,5,6-tetrachloro-1,4-benzoquinone + chloride + NADP(+) + H2O

Direction not assertedBalancedRhea 18685

a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 18689

a penicillin + H2O = 6-aminopenicillanate + a carboxylate

Direction not assertedBalance undeterminableRhea 18693

3-(4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO2

Direction not assertedBalancedRhea 18697

2 oxidized [azurin] + arsenite + H2O = 2 reduced [azurin] + arsenate + 3 H(+)

Direction not assertedBalance undeterminableRhea 18701

a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl derivative + UDP + H(+)

Direction not assertedBalance undeterminableRhea 18705

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