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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
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Reactions
Reach

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Processes
Anatomy
Cell types
Organisms
Materials
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Diseases

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

14,851–14,900 of 31,435, by identifier

a phtalamide + H2O = phthalate + a primary amine
Direction not assertedBalance undeterminableRhea 18297
XMP + NH4(+) + ATP = GMP + AMP + diphosphate + 2 H(+)
Direction not assertedBalancedRhea 18301
N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA
Direction not assertedBalancedRhea 18305
an N-acyl-D-amino acid + H2O = a D-alpha-amino acid + a carboxylate
Direction not assertedBalance undeterminableRhea 18309
(R)-mandelonitrile = benzaldehyde + hydrogen cyanide
Direction not assertedBalancedRhea 18313
an L-alpha-amino acid = a D-alpha-amino acid
Direction not assertedBalance undeterminableRhea 18317
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate

Left to rightBalancedRhea 18321

(2E,6E)-farnesyl diphosphate = (+)-amorpha-4,11-diene + diphosphate

Direction not assertedBalancedRhea 18325

(1S,3R,5S)-sabinol + NAD(+) = (1S,5S)-sabinone + NADH + H(+)

Direction not assertedBalancedRhea 18329

oleandomycin + ATP = oleandomycin 2'-O-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 18333

D-ribose 5-phosphate + uracil = psi-UMP + H2O

Direction not assertedBalancedRhea 18337

D-xylono-1,4-lactone + H2O = D-xylonate + H(+)

Direction not assertedBalancedRhea 18341

a cis-3-alkyl-4-alkyloxetan-2-one = a cis-alkene + CO2

Direction not assertedBalance undeterminableRhea 18345

tRNA(Asx) + L-aspartate + ATP = L-aspartyl-tRNA(Asx) + AMP + diphosphate

Direction not assertedBalancedRhea 18349

2 K(+)(out) + 3 Na(+)(in) + ATP + H2O = 2 K(+)(in) + 3 Na(+)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 18353

tropine + NADP(+) = tropinone + NADPH + H(+)

Direction not assertedBalancedRhea 18357

a di-trans,poly-cis-dolichyl D-xylosyl phosphate + L-seryl-[protein] = 3-O-(beta-D-xylosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)

Direction not assertedBalance undeterminableRhea 18361

(R)-malate + NAD(+) = pyruvate + CO2 + NADH

Direction not assertedBalancedRhea 18365

sn-glycerol 3-phosphate + O2 = dihydroxyacetone phosphate + H2O2

Direction not assertedBalancedRhea 18369

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+)

Left to rightBalance undeterminableRhea 18373

streptomycin + ATP = streptomycin 3''-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 18377

dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate

Direction not assertedBalancedRhea 18381

acetone + hydrogencarbonate + 2 ATP + 3 H2O = acetoacetate + 2 AMP + 4 phosphate + 4 H(+)

Direction not assertedBalancedRhea 18385

alpha-D-xylose 1-phosphate + UTP + H(+) = UDP-alpha-D-xylose + diphosphate

Direction not assertedBalancedRhea 18389

(R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine

Left to rightBalancedRhea 18393

tRNA(Glx) + L-glutamate + ATP = L-glutamyl-tRNA(Glx) + AMP + diphosphate

Left to rightBalancedRhea 18397

(E)-4-hydroxyphenylacetaldehyde oxime + reduced [NADPH--hemoprotein reductase] + O2 = (S)-4-hydroxymandelonitrile + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 18401

L-alanine + NAD(+) + H2O = pyruvate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 18405

4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADP(+) = 4alpha-methyl-5alpha-cholest-7-en-3-one + NADPH + H(+)

Right to leftBalancedRhea 18409

a beta-D-galactosyl-(1->4)-beta-D-glucosyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosaminyl derivative + UDP + H(+)

Direction not assertedBalance undeterminableRhea 18413

a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM3 (d18:1(4E)) + CMP + H(+)

Left to rightBalance undeterminableRhea 18417

chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA

Direction not assertedBalancedRhea 18421

L-quinate + NADP(+) = 3-dehydroquinate + NADPH + H(+)

Direction not assertedBalancedRhea 18425

cyclohexylamine + O2 + H2O = cyclohexanone + H2O2 + NH4(+)

Direction not assertedBalancedRhea 18433

4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 18437

D-dopachrome + H(+) = 5,6-dihydroxyindole + CO2

Left to rightBalancedRhea 18441

IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

Right to leftBalancedRhea 18445

arsenite + A + H2O = arsenate + AH2 + H(+)

Direction not assertedBalancedRhea 18449

[(1->2)-beta-D-glucosyl](n)(in) + ATP + H2O = [(1->2)-beta-D-glucosyl](n)(out) + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableTransportRhea 18453

D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)

Direction not assertedBalancedRhea 18457

a 1-O-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalance undeterminableRhea 18461

L-dopa + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)

Direction not assertedBalancedRhea 18465

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 18469

1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP

Direction not assertedBalancedRhea 18473

2,3-dihydroxybenzoate + O2 = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+)

Direction not assertedBalancedRhea 18477

cyclohexylsulfamate + H2O = cyclohexylamine + sulfate

Direction not assertedBalancedRhea 18481

6-acetyl-D-glucose + H2O = D-glucose + acetate + H(+)

Direction not assertedBalancedRhea 18485

cyanate + hydrogencarbonate + H(+) = carbamate + CO2

Direction not assertedBalancedRhea 18489

benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+)

Direction not assertedBalancedRhea 18493

L-ribulose 5-phosphate = L-xylulose 5-phosphate

Direction not assertedBalancedRhea 18497

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