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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

14,351–14,400 of 31,435, by identifier

an (R)-2-haloacid + H2O = a (2R)-2-hydroxycarboxylate + a halide anion + H(+)
Direction not assertedBalance undeterminableRhea 16193
(3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + NADPH + H(+)
Direction not assertedBalancedRhea 16197
4-amino-4-deoxychorismate = 4-aminobenzoate + pyruvate + H(+)
Direction not assertedBalancedRhea 16201
N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein] + H2O = N(6)-(D-fructosyl)-L-lysyl-[protein] + phosphate
Direction not assertedBalance undeterminableRhea 16205
Co-precorrin-8X = cob(II)yrinate
Direction not assertedBalancedRhea 16209
3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+)
Left to right

→

Balance undeterminable

Rhea 16213

L-arabinono-1,4-lactone + H2O = L-arabinonate + H(+)

Direction not assertedBalancedRhea 16217

3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 16221

1,8-diazacyclotetradecane-2,9-dione + H2O = N-(6-aminohexanoyl)-6-aminohexanoate

Direction not assertedBalancedRhea 16225

a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate

Left to rightBalance undeterminableRhea 16229

(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)

Direction not assertedBalancedRhea 16233

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Direction not assertedBalance undeterminableRhea 16237

an NDP-alpha-D-glucose + D-fructose = a ribonucleoside 5'-diphosphate + sucrose + H(+)

Direction not assertedBalance undeterminableRhea 16241

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalance undeterminableRhea 16245

alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate

ReversibleBalancedRhea 16249

(3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = phenanthrene-3,4-diol + NADH + H(+)

Direction not assertedBalancedRhea 16253

alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 16257

succinyl-CoA + L-lysyl-[protein] = N(6)-succinyl-L-lysyl-[protein] + CoA + H(+)

Left to rightBalance undeterminableRhea 16261

trans-5-O-(4-coumaroyl)-D-quinate + reduced [NADPH--hemoprotein reductase] + O2 = 5-O-[(E)-caffeoyl]-D-quinate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 16265

N,N-dimethyl-1,4-phenylenediamine + aniline + 2 NADP(+) = 4-(dimethylamino)azobenzene + 2 NADPH + 2 H(+)

Direction not assertedBalancedRhea 16269

CDP-choline + an N-acylsphing-4-enine = a sphingomyelin + CMP + H(+)

Direction not assertedBalance undeterminableRhea 16273

indole-3-acetaldehyde + O2 + H2O = (indol-3-yl)acetate + H2O2 + H(+)

Direction not assertedBalancedRhea 16277

dihydrostreptomycin 6-phosphate + ATP = dihydrostreptomycin 3'alpha,6-bisphosphate + ADP + H(+)

Direction not assertedBalancedRhea 16281

D-octopine + NAD(+) + H2O = L-arginine + pyruvate + NADH + H(+)

Direction not assertedBalancedRhea 16285

(1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + NADH + 2 H(+)

Direction not assertedBalancedRhea 16289

2-isopropylmaleate + H2O = (2S)-2-isopropylmalate

Direction not assertedBalancedRhea 16293

5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H(+)

Right to leftBalancedRhea 16297

NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+)

Left to rightBalancedRhea 16301

(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+)

Left to rightBalancedRhea 16305

taurochenodeoxycholate + H2O = chenodeoxycholate + taurine

Direction not assertedBalancedRhea 16309

5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+)

Direction not assertedBalancedRhea 16313

(S)-indan-1-ol + NAD(+) = indan-1-one + NADH + H(+)

Direction not assertedBalancedRhea 16317

(S)-indan-1-ol + NADP(+) = indan-1-one + NADPH + H(+)

Direction not assertedBalancedRhea 16321

1-phospho-alpha-D-glucuronate + UTP + H(+) = UDP-alpha-D-glucuronate + diphosphate

Direction not assertedBalancedRhea 16325

(9Z,12Z,15Z)-octadecatrienoate + O2 = (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 16329

apo-[citrate lyase ACP] + 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA = holo-[citrate lyase ACP] + diphosphate

Direction not assertedBalance undeterminableRhea 16333

a 3'-unsubstituted flavone + reduced [NADPH--hemoprotein reductase] + O2 = a 3'-hydroxyflavone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 16337

(R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP

ReversibleBalancedRhea 16341

(2E,6E,10E)-geranylgeranyl diphosphate + H2O = (3E,7E)-dolabella-3,7-dien-18-ol + diphosphate

Direction not assertedBalancedRhea 16345

chlorate + AH2 = chlorite + A + H2O

Direction not assertedBalancedRhea 16349

taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate

Direction not assertedBalancedRhea 16353

succinate + A = fumarate + AH2

Direction not assertedBalancedRhea 16357

2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate

Direction not assertedBalancedRhea 16361

digallate + H2O = 2 3,4,5-trihydroxybenzoate + H(+)

Direction not assertedBalancedRhea 16365

(R)-lactate + NAD(+) = pyruvate + NADH + H(+)

Direction not assertedBalancedRhea 16369

(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)

Direction not assertedBalancedRhea 16373

(3Z)-phytochromobilin + 2 oxidized [2Fe-2S]-[ferredoxin] = biliverdin IXalpha + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)

Direction not assertedBalance undeterminableRhea 16377

L-arabinitol + NAD(+) = L-xylulose + NADH + H(+)

Direction not assertedBalancedRhea 16381

4-hydroxybenzoate + NADPH + O2 + 2 H(+) = hydroquinone + CO2 + NADP(+) + H2O

Direction not assertedBalancedRhea 16385

4-hydroxybenzoate + NADH + O2 + 2 H(+) = hydroquinone + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 16389

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