Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

14,301–14,350 of 31,435, by identifier

formate + NAD(+) = CO2 + NADH
Direction not assertedBalancedRhea 15985
(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)
Right to leftBalancedRhea 15989
anthraniloyl-CoA + 2 NADPH + O2 + 2 H(+) = 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 NADP(+) + H2O
Direction not assertedBalancedRhea 15993
anthraniloyl-CoA + 2 NADH + O2 + 2 H(+) = 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 NAD(+) + H2O
Direction not assertedBalancedRhea 15997
N(6)-methyl-AMP + H2O + H(+) = IMP + methylamine
Left to rightBalancedRhea 16001
galactarate = 5-dehydro-4-deoxy-D-glucarate + H2O
Direction not assertedBalancedRhea 16005
formate + ATP = formyl phosphate + ADP

? Direction not asserted

Balanced

Rhea 16009

tRNA(Gly) + glycine + ATP = glycyl-tRNA(Gly) + AMP + diphosphate

Left to rightBalancedRhea 16013

oxaloacetate = enol-oxaloacetate

Right to leftBalancedRhea 16021

an anthocyanidin 3-O-beta-D-glucoside + malonyl-CoA = an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA

Direction not assertedBalance undeterminableRhea 16025

3-guanidinopropanoate + H2O = urea + beta-alanine

Left to rightBalancedRhea 16029

gibberellin A44 + 2-oxoglutarate + O2 = gibberellin A19 + succinate + CO2 + H2O

Direction not assertedBalancedRhea 16033

thymidine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + thymine

Left to rightBalancedRhea 16037

[(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate

Direction not assertedBalance undeterminableRhea 16041

a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 16045

alpha-ribazole + adenosylcob(III)inamide-GDP = adenosylcob(III)alamin + GMP + H(+)

Direction not assertedBalancedRhea 16049

UDP-N-acetyl-alpha-D-mannosamine + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 16053

N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 16057

sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)

Left to rightBalancedRhea 16061

phytanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyphytanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 16065

cytidine + H2O + H(+) = uridine + NH4(+)

Direction not assertedBalancedRhea 16069

2,2-dialkylglycine + pyruvate + H(+) = dialkyl ketone + L-alanine + CO2

Direction not assertedBalance undeterminableRhea 16073

(2R)-S-methyl-3-phospho-1-thioglycerate + H2O = (2R)-S-methyl-1-thioglycerate + phosphate

Direction not assertedBalancedRhea 16081

UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine + ATP = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 16085

phosphoethanolamine + H2O = ethanolamine + phosphate

Left to rightBalancedRhea 16089

(24R)-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 = (24R)-7alpha-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 16093

acetylpyruvate + H2O = acetate + pyruvate + H(+)

Direction not assertedBalancedRhea 16097

chondroitin beta-D-glucuronate + n 3'-phosphoadenylyl sulfate = chondroitin 4'-sulfate + n adenosine 3',5'-bisphosphate + n H(+)

Direction not assertedBalance undeterminableRhea 16101

a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O

ReversibleBalance undeterminableRhea 16105

beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)

Left to rightBalancedRhea 16109

2 cob(II)alamin-[cyanocobalamin reductase] + 2 hydrogen cyanide + NADP(+) = 2 cyanocob(III)alamin + 2 apo-[cyanocobalamin reductase] + NADPH + H(+)

Right to leftBalance undeterminableRhea 16113

acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 16117

5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+)

Direction not assertedBalancedRhea 16121

D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)

Left to rightBalancedRhea 16125

pyridoxine + NADP(+) = pyridoxal + NADPH + H(+)

Direction not assertedBalancedRhea 16129

N(1)-acetylspermine + O2 + H2O = N(1)-acetylspermidine + 3-aminopropanal + H2O2

Direction not assertedBalancedRhea 16133

2'-deoxymugineate + NADP(+) = 3''-deamino-3''-oxonicotianamine + NADPH + H(+)

Direction not assertedBalancedRhea 16137

2'-deoxymugineate + NAD(+) = 3''-deamino-3''-oxonicotianamine + NADH + H(+)

Direction not assertedBalancedRhea 16141

CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = CMP-N-glycoloyl-beta-neuraminate + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 16145

beta-nicotinamide D-ribonucleotide + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + nicotinamide + H(+)

Right to leftBalancedRhea 16149

a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)

Left to rightBalance undeterminableRhea 16153

2 Fe(III)-[leghemoglobin] + NADPH = 2 Fe(II)-[leghemoglobin] + NADP(+) + H(+)

Direction not assertedBalance undeterminableRhea 16157

2 Fe(III)-[leghemoglobin] + NADH = 2 Fe(II)-[leghemoglobin] + NAD(+) + H(+)

Direction not assertedBalance undeterminableRhea 16161

L-tryptophan + O2 = indole-3-acetamide + CO2 + H2O

Direction not assertedBalancedRhea 16165

L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 16169

(4-hydroxyphenyl)acetaldehyde + dopamine = (S)-norcoclaurine + H2O

Direction not assertedBalancedRhea 16173

retinal + NAD(+) + H2O = retinoate + NADH + 2 H(+)

Left to rightBalancedRhea 16177

3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 16181

an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)

Left to rightBalance undeterminableRhea 16185

3-(4-hydroxyphenyl)pyruvate + O2 = homogentisate + CO2

Left to rightBalancedRhea 16189

Page 287 of 629