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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

13,751–13,800 of 31,435, by identifier

lathosterol + NADP(+) = 5alpha-cholesta-7,24-dien-3beta-ol + NADPH + H(+)
Direction not assertedBalancedRhea 13685
glycerol + diphosphate = glycerol 1-phosphate + phosphate + H(+)
Direction not assertedBalancedRhea 13689
trimethylsulfonium + (6S)-5,6,7,8-tetrahydrofolate = dimethyl sulfide + (6S)-5-methyl-5,6,7,8-tetrahydrofolate + H(+)
Direction not assertedBalancedRhea 13693
D-ribose + ATP = D-ribose 5-phosphate + ADP + H(+)
Direction not assertedBalancedRhea 13697
L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA
Direction not assertedBalancedRhea 13701
alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + UDP-N-acetyl-alpha-D-glucosamine = alpha-D-Man-(1->3)-[alpha-D-GlcNAc-(1->2)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + UDP + H(+)
Direction not assertedBalancedRhea 13705

a ubiquinone + succinate = a ubiquinol + fumarate

Direction not assertedBalance undeterminableRhea 13713

2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 13717

testololactone + H2O = testolate + H(+)

Direction not assertedBalancedRhea 13721

alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H(+)

Direction not assertedBalancedRhea 13725

FAD = riboflavin cyclic-4',5'-phosphate + AMP + H(+)

Direction not assertedBalancedRhea 13729

an n-alkanal + NAD(+) = an alk-2-enal + NADH + H(+)

Direction not assertedBalance undeterminableRhea 13733

an n-alkanal + NADP(+) = an alk-2-enal + NADPH + H(+)

Right to leftBalance undeterminableRhea 13737

3-phenylpyruvate + L-tryptophan = indole-3-pyruvate + L-phenylalanine

Direction not assertedBalancedRhea 13741

ascopyrone M = microthecin

Direction not assertedBalancedRhea 13745

a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP

Direction not assertedBalance undeterminableRhea 13749

2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)

Direction not assertedBalancedRhea 13753

(Z)-2-phenyl-1-thioacetohydroximate + UDP-alpha-D-glucose = (Z)-desulfoglucotropeolin + UDP

Direction not assertedBalancedRhea 13757

L-methionine + S-adenosyl-L-methionine = S-methyl-L-methionine + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 13761

bromochloromethane + H2O = bromide + formaldehyde + chloride + 2 H(+)

Direction not assertedBalancedRhea 13765

glycerol + NAD(+) = dihydroxyacetone + NADH + H(+)

Direction not assertedBalancedRhea 13769

(S)-cheilanthifoline + reduced [NADPH--hemoprotein reductase] + O2 = (S)-stylopine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 13773

D-ribose 5-phosphate + NH4(+) + ATP = 5-phospho-beta-D-ribosylamine + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 13777

an L-alpha-amino acid + O2 + H2O = a 2-oxocarboxylate + H2O2 + NH4(+)

Left to rightBalance undeterminableRhea 13781

(3S)-citramalyl-CoA = itaconyl-CoA + H2O

Right to leftBalancedRhea 13785

[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose = alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)

Direction not assertedBalance undeterminableRhea 13789

2-methyleneglutarate = 2-methylene-3-methylsuccinate

Direction not assertedBalancedRhea 13793

a di-trans,poly-cis-dolichyl phosphate + H2O = a di-trans,poly-cis-dolichol + phosphate

Direction not assertedBalance undeterminableRhea 13797

hydrogen sulfide + 3 NADP(+) + 3 H2O = sulfite + 3 NADPH + 4 H(+)

Direction not assertedBalancedRhea 13801

a 3-oxo-5alpha-steroid + A = a 3-oxo-Delta(4)-steroid + AH2

Direction not assertedBalance undeterminableRhea 13805

aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate

Direction not assertedBalancedRhea 13809

benzene + NADH + O2 + H(+) = cis-1,2-dihydrobenzene-1,2-diol + NAD(+)

Direction not assertedBalancedRhea 13813

phylloquinone + [protein]-disulfide + H2O = 2,3-epoxyphylloquinone + [protein]-dithiol

Right to leftBalance undeterminableRhea 13817

glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2

Direction not assertedBalancedRhea 13821

GDP-alpha-D-rhamnose + NAD(+) = GDP-4-dehydro-alpha-D-rhamnose + NADH + H(+)

Direction not assertedBalancedRhea 13825

GDP-alpha-D-rhamnose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH + H(+)

Direction not assertedBalancedRhea 13829

L-arginine + pyruvate = 5-guanidino-2-oxopentanoate + L-alanine

Direction not assertedBalancedRhea 13833

cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + NADH + H(+)

Direction not assertedBalancedRhea 13837

Fe(II)2-[transferrin] + NAD(+) + H(+) = Fe(III)2-[transferrin] + NADH

Direction not assertedBalance undeterminableRhea 13841

dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO2

Direction not assertedBalancedRhea 13845

D-arabinose = D-ribulose

Direction not assertedBalancedRhea 13849

4-methylene-L-glutamate + NH4(+) + ATP = 4-methylene-L-glutamine + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 13853

a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + D-glucose + H(+)

Direction not assertedBalance undeterminableRhea 13857

D-xylose + NAD(+) = D-xylono-1,5-lactone + NADH + H(+)

Direction not assertedBalancedRhea 13861

an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)

Left to rightBalance undeterminableRhea 13865

prephenate + NAD(+) = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADH

Direction not assertedBalancedRhea 13869

(+)-copalyl diphosphate = abieta-7,13-diene + diphosphate

Direction not assertedBalancedRhea 13873

a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid

Direction not assertedBalance undeterminableRhea 13877

an aldehyde + a quinone + H2O = a quinol + a carboxylate + H(+)

Direction not assertedBalance undeterminableRhea 13881

stipitatonate + H2O = stipitatate + CO2

Direction not assertedBalancedRhea 13885

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