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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

13,551–13,600 of 31,435, by identifier

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
Direction not assertedBalancedRhea 12821
acetyl phosphate + methylamine + [thioredoxin]-disulfide + H2O = sarcosine + [thioredoxin]-dithiol + phosphate + H(+)
Direction not assertedBalance undeterminableRhea 12825
(2S,3S)-3-methyl-L-aspartate = mesaconate + NH4(+)
Direction not assertedBalancedRhea 12829
an N-acyl-D-glutamate + H2O = D-glutamate + a carboxylate
Direction not assertedBalance undeterminableRhea 12833
choline + ATP = phosphocholine + ADP + H(+)
Left to rightBalancedRhea 12837
pyridoxamine + pyruvate = pyridoxal + L-alanine
Direction not assertedBalancedRhea 12841
[L-4-(L-arginin-2-N-yl)aspartate](n) + H2O = [L-4-(L-arginin-2-N-yl)aspartate](n-1) + L-4-(L-arginin-2-N-yl)aspartate

Direction not assertedBalance undeterminableRhea 12845

O-phospho-L-seryl-[myosin light chain] + H2O = L-seryl-[myosin light chain] + phosphate

Direction not assertedBalance undeterminableRhea 12849

(S)-4-hydroxymandelonitrile + UDP-alpha-D-glucose = dhurrin + UDP + H(+)

Direction not assertedBalancedRhea 12853

(2S,3S)-3-methyl-L-aspartate = L-glutamate

Direction not assertedBalancedRhea 12857

guanosine + H2O + H(+) = xanthosine + NH4(+)

Direction not assertedBalancedRhea 12861

1-methyladenosine + H2O = 1-methyladenine + D-ribose

Direction not assertedBalancedRhea 12865

(2E)-geranyl diphosphate = (4S)-limonene + diphosphate

Direction not assertedBalancedRhea 12869

(2R)-hydroxy-4-methylpentanoate + NADP(+) = 4-methyl-2-oxopentanoate + NADPH + H(+)

Direction not assertedBalancedRhea 12873

acetylacetone + O2 = methylglyoxal + acetate + H(+)

Direction not assertedBalancedRhea 12877

ADP-alpha-D-glucose + sn-glycerol 3-phosphate = 2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 12881

queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-mannosylqueuosine(34) in tRNA(Asp) + GDP + H(+)

Left to rightBalancedRhea 12885

L-gulonate + NAD(+) = 3-dehydro-L-gulonate + NADH + H(+)

Left to rightBalancedRhea 12889

prostaglandin H2 = prostaglandin E2

Left to rightBalancedRhea 12893

2-cis-(+)-abscisate + reduced [NADPH--hemoprotein reductase] + O2 = (+)-8'-hydroxyabscisate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 12897

D-arginine + H2O = D-ornithine + urea

Direction not assertedBalancedRhea 12901

alpha-D-mannose 1-phosphate + GDP + H(+) = GDP-alpha-D-mannose + phosphate

Direction not assertedBalancedRhea 12905

2 Fe(II)-[cytochrome] + nitrate + 2 H(+) = 2 Fe(III)-[cytochrome] + nitrite + H2O

Direction not assertedBalance undeterminableRhea 12909

(R)-lipoate + ATP + H(+) = (R)-lipoyl-5'-AMP + diphosphate

Direction not assertedBalancedRhea 12913

3alpha(S)-strictosidine + H2O = strictosidine aglycone + D-glucose

Direction not assertedBalancedRhea 12917

succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA

Left to rightBalancedRhea 12921

D-erythrose 4-phosphate + L-lysyl-[protein] = N(6)-(4-O-phospho-D-erythrulosyl)-L-lysyl-[protein] + H2O

Direction not assertedBalance undeterminableRhea 12925

acetyl-CoA + 2-oxoglutarate + H2O = (2R)-homocitrate + CoA + H(+)

Direction not assertedBalancedRhea 12929

L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate

Direction not assertedBalancedRhea 12933

a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA

Left to rightBalance undeterminableRhea 12937

an N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 12941

2'-hydroxybiphenyl-2-sulfinate + H2O = biphenyl-2-ol + sulfite + H(+)

Direction not assertedBalancedRhea 12945

D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H2O

Direction not assertedBalancedRhea 12949

L-seryl-[Goodpasture antigen-binding protein] + ATP = O-phospho-L-seryl-[Goodpasture antigen-binding protein] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 12953

an acetyl ester + H2O = an aliphatic alcohol + acetate + H(+)

Left to rightBalance undeterminableRhea 12957

acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate

Direction not assertedBalancedRhea 12961

D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + H(+)

Direction not assertedBalancedRhea 12965

a sn-glycero-3-phosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate + H(+)

Direction not assertedBalance undeterminableRhea 12969

AMP + ATP = 2 ADP

Direction not assertedBalancedRhea 12973

N-phosphocreatine + H2O = creatine + phosphate

Left to rightBalancedRhea 12977

S-sulfanylglutathione + O2 + H2O = sulfite + glutathione + 2 H(+)

Direction not assertedBalancedRhea 12981

N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + GDP-beta-L-fucose = an N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc}-L-asparaginyl-[protein] + GDP + H(+)

Left to rightBalance undeterminableRhea 12985

a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + H2O = D-mannose + a di-trans,poly-cis-dolichyl phosphate + H(+)

Direction not assertedBalance undeterminableRhea 12989

cyclohex-1-ene-1-carbonyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = cyclohexa-1,5-diene-1-carbonyl-CoA + reduced [electron-transfer flavoprotein]

Direction not assertedBalance undeterminableRhea 12993

galactarate + (E)-feruloyl-CoA = 2-O-[(E)-feruloyl]-D-galactarate + CoA

Direction not assertedBalancedRhea 12997

1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate

Direction not assertedBalancedRhea 13001

(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-methionine = N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 13005

N-formyl-L-kynurenine + H2O = L-kynurenine + formate + H(+)

Direction not assertedBalancedRhea 13009

a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = an alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)

Left to rightBalance undeterminableRhea 13013

UMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + uracil

Direction not assertedBalancedRhea 13017

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