Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

13,451–13,500 of 31,435, by identifier

(2R)-3-phosphoglycerate + H2O = (R)-glycerate + phosphate
Direction not assertedBalancedRhea 12412
beta-alanyl-CoA = acryloyl-CoA + NH4(+)
Direction not assertedBalancedRhea 12416
D-tagatofuranose 6-phosphate + ATP = D-tagatofuranose 1,6-bisphosphate + ADP + H(+)
Direction not assertedBalancedRhea 12420
(3S)-3-hydroxy-L-aspartate = oxaloacetate + NH4(+)
Direction not assertedBalancedRhea 12424
2-hydroxy-1,4-benzoquinone + NADH + 2 H(+) = benzene-1,2,4-triol + NAD(+)
Direction not assertedBalancedRhea 12428
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA(Ala) = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA(Ala) + H(+)
Direction not assertedBalancedRhea 12432

(E)-caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+)

Direction not assertedBalancedRhea 12436

L-saccharopine + NAD(+) + H2O = L-lysine + 2-oxoglutarate + NADH + H(+)

Direction not assertedBalancedRhea 12440

hexadecanal + NADP(+) = (2E)-hexadecenal + NADPH + H(+)

Direction not assertedBalancedRhea 12444

(R)-pantothenate + H2O = (R)-pantoate + beta-alanine

Direction not assertedBalancedRhea 12448

1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)

ReversibleBalancedRhea 12452

D-ribitol 5-phosphate + CTP + H(+) = CDP-L-ribitol + diphosphate

Direction not assertedBalancedRhea 12456

(S)-malate = fumarate + H2O

ReversibleBalancedRhea 12460

myo-inositol + UDP-alpha-D-galactose = alpha-D-galactosyl-(1->3)-1D-myo-inositol + UDP + H(+)

Direction not assertedBalancedRhea 12464

avenacoside A + H2O = 26-desgluco-avenacoside A + D-glucose

Direction not assertedBalancedRhea 12468

N-ethylglycine + O2 + H2O = ethylamine + glyoxylate + H2O2

Direction not assertedBalancedRhea 12472

N-formyl-L-glutamate + H2O = formate + L-glutamate

Direction not assertedBalancedRhea 12476

5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine

Direction not assertedBalancedRhea 12480

a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate

Left to rightBalance undeterminableRhea 12484

2-amino-2-deoxy-D-gluconate = 2-dehydro-3-deoxy-D-gluconate + NH4(+)

Direction not assertedBalancedRhea 12488

L-methionine = D-methionine

Direction not assertedBalancedRhea 12492

2 Fe(2+) + O2 + 4 H2O = 2 iron(III) oxide-hydroxide + H2O2 + 6 H(+)

Direction not assertedBalancedRhea 12496

(3R)-1,4-thiomorpholine-3-carboxylate + NADP(+) = 3,4-dehydrothiomorpholine-3-carboxylate + NADPH + 2 H(+)

Right to leftBalancedRhea 12500

(3R)-1,4-thiomorpholine-3-carboxylate + NAD(+) = 3,4-dehydrothiomorpholine-3-carboxylate + NADH + 2 H(+)

Right to leftBalancedRhea 12504

loganate + S-adenosyl-L-methionine = loganin + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 12508

D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)

Left to rightBalancedRhea 12512

(2E,6E)-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate

Direction not assertedBalancedRhea 12516

L-dopa = (E)-caffeate + NH4(+)

Direction not assertedBalancedRhea 12520

L-pipecolate + NADP(+) = Delta(1)-piperideine-2-carboxylate + NADPH + H(+)

Right to leftBalancedRhea 12524

N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP-alpha-D-glucuronate = [hyaluronan](n+1) + UDP + H(+)

Left to rightBalance undeterminableRhea 12528

coenzyme B + methyl-coenzyme M = methane + coenzyme M-coenzyme B heterodisulfide

Direction not assertedBalancedRhea 12532

L-arogenate + H(+) = L-phenylalanine + CO2 + H2O

Direction not assertedBalancedRhea 12536

tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate

Direction not assertedBalancedRhea 12540

hydrogenobyrinate + 2 L-glutamine + 2 ATP + 2 H2O = hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 ADP + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 12544

2-cis,4-trans-xanthoxin + NAD(+) = 2-cis-(+)-abscisic aldehyde + NADH + H(+)

Direction not assertedBalancedRhea 12548

(E)-cinnamoyl-CoA + 3 malonyl-CoA + 3 H(+) = (E)-pinosylvin + 4 CO2 + 4 CoA

Direction not assertedBalancedRhea 12552

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)

Left to rightBalancedRhea 12556

hydroquinone + UDP-alpha-D-glucose = hydroquinone O-beta-D-glucopyranoside + UDP + H(+)

Direction not assertedBalancedRhea 12560

4-nitrophenol + NADH + O2 + H(+) = 4-nitrocatechol + NAD(+) + H2O

Direction not assertedBalancedRhea 12568

(R)-1-aminopropan-2-ol + adenosylcob(III)yrate + ATP = adenosylcob(III)inamide + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 12572

(5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + UDP-alpha-D-glucose = (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 12576

tauropine + NAD(+) + H2O = taurine + pyruvate + NADH + H(+)

Direction not assertedBalancedRhea 12580

16alpha-hydroxyprogesterone = 16,17-didehydroprogesterone + H2O

Direction not assertedBalancedRhea 12584

a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 (d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 12588

a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 12593

L-phosphinothricin + acetyl-CoA = N-acetyl-L-phosphinothricin + CoA + H(+)

Direction not assertedBalancedRhea 12597

L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate

Left to rightBalancedRhea 12601

D-glyceraldehyde 3-phosphate + pyruvate + H(+) = 1-deoxy-D-xylulose 5-phosphate + CO2

Direction not assertedBalancedRhea 12605

mercaptopurine + S-adenosyl-L-methionine = 6-methylthiopurine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 12609

L-cystine + 2 glutathione = glutathione disulfide + 2 L-cysteine

Direction not assertedBalancedRhea 12613

Page 270 of 629