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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

13,201–13,250 of 31,435, by identifier

(19E)-geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + NADPH
Direction not assertedBalancedRhea 11376
[2-(trimethylamino)ethyl]phosphonate + 2-oxoglutarate + O2 = [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + succinate + CO2
Direction not assertedBalancedRhea 11380
(S)-2-hydroxyoctadecanoate + NAD(+) = 2-oxooctadecanoate + NADH + H(+)
Direction not assertedBalancedRhea 11384
an 11beta-hydroxysteroid + NADP(+) = an 11-oxosteroid + NADPH + H(+)
ReversibleBalance undeterminableRhea 11388
1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate
Left to rightBalancedRhea 11392
5-methyldeoxycytidine 5'-phosphate + ATP = 5-methyldeoxycytidine diphosphate + ADP
Direction not assertedBalancedRhea 11396
sordaricin + GDP-6-deoxy-alpha-D-altrose = 4'-O-demethylsordarin + GDP + H(+)

Direction not assertedBalancedRhea 11400

UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate

Direction not assertedBalancedRhea 11404

riboflavin + H2O + H(+) = lumichrome + ribitol

Direction not assertedBalancedRhea 11408

6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)

Direction not assertedBalancedRhea 11412

2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose

Direction not assertedBalancedRhea 11416

senecionine + NADPH + O2 = senecionine N-oxide + NADP(+) + H2O

Direction not assertedBalancedRhea 11420

L-threonyl-[myosin heavy-chain] + ATP = O-phospho-L-threonyl-[myosin heavy-chain] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 11424

beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 11428

vitexin 2''-O-beta-L-rhamnoside + S-adenosyl-L-methionine = 7-O-methylvitexin 2''-O-beta-L-rhamnoside + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 11432

4 Fe(II)-[cytochrome c] + O2 + 8 H(+)(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H(+)(out)

Left to rightBalance undeterminableTransportRhea 11436

2,3,5,6-tetrachlorophenol + NADPH + O2 = 2,3,5,6-tetrachlorohydroquinone + NADP(+) + H2O

Direction not assertedBalancedRhea 11440

4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + sulfate + H(+)

Direction not assertedBalancedRhea 11444

pregnan-21-ol + NAD(+) = pregnan-21-al + NADH + H(+)

Direction not assertedBalancedRhea 11448

7-deoxyloganin + reduced [NADPH--hemoprotein reductase] + O2 = loganin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 11452

N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 11456

D-glucose + ADP = D-glucose 6-phosphate + AMP + H(+)

Direction not assertedBalancedRhea 11460

L,L-homocystine + 2 glutathione = 2 L-homocysteine + glutathione disulfide

Direction not assertedBalancedRhea 11464

(S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine

Direction not assertedBalancedRhea 11468

an N-methyl-L-amino acid + O2 + H2O = an L-alpha-amino acid + formaldehyde + H2O2

Direction not assertedBalance undeterminableRhea 11472

glycerol 1-phosphate + H2O = glycerol + phosphate

Direction not assertedBalancedRhea 11476

3-hydroxybenzoate + NADPH + O2 + H(+) = 3,4-dihydroxybenzoate + NADP(+) + H2O

Direction not assertedBalancedRhea 11480

a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)

Direction not assertedBalance undeterminableRhea 11484

all-trans-retinol + an acyl-CoA = an all-trans-retinyl ester + CoA

Left to rightBalance undeterminableRhea 11488

O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO2

Direction not assertedBalancedRhea 11492

O-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate + H(+)

Direction not assertedBalancedRhea 11496

3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + H2O = 3-deoxy-alpha-D-manno-oct-2-ulosonate + phosphate

Direction not assertedBalancedRhea 11500

6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 11504

L-aspartyl-[protein] + 2-oxoglutarate + O2 = 3-hydroxy-L-aspartyl-[protein] + succinate + CO2

Direction not assertedBalance undeterminableRhea 11508

salicyl alcohol + UDP-alpha-D-glucose = salicin + UDP + H(+)

Direction not assertedBalancedRhea 11512

succinyl-CoA + H2O = succinate + CoA + H(+)

Left to rightBalancedRhea 11516

(-)-menthol + UDP-alpha-D-glucose = (-)-menthyl beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 11520

5beta-cholestan-3-one + NADP(+) = cholest-4-en-3-one + NADPH + H(+)

Right to leftBalancedRhea 11524

2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] + 2 ATP = 2 adenosylcob(III)yrinate a,c-diamide + 2 triphosphate + oxidized [electron-transfer flavoprotein] + 3 H(+)

Direction not assertedBalance undeterminableRhea 11528

glycine + O2 + H2O = glyoxylate + H2O2 + NH4(+)

Direction not assertedBalancedRhea 11532

choline + 2 O2 + H2O = glycine betaine + 2 H2O2 + H(+)

Direction not assertedBalancedRhea 11536

an N-acyl-D-mannosamine + NAD(+) = an N-acyl-D-mannosaminolactone + NADH + H(+)

Direction not assertedBalance undeterminableRhea 11540

N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+)

Direction not assertedBalancedRhea 11544

5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+)

Direction not assertedBalancedRhea 11548

a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)

Left to rightBalance undeterminableRhea 11552

(S)-carnitine + NAD(+) = 3-dehydrocarnitine + NADH + H(+)

Direction not assertedBalancedRhea 11556

(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+) = catechol + CO2 + NADH

Direction not assertedBalancedRhea 11560

4-O-beta-D-glucopyranosyl-D-gluconate + phosphate = D-gluconate + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 11564

dCMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 5-methyldeoxycytidine 5'-phosphate + 7,8-dihydrofolate

Direction not assertedBalancedRhea 11568

lithocholate + FAD + H2O + H(+) = chenodeoxycholate + FADH2

Direction not assertedBalancedRhea 11572

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