Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

13,101–13,150 of 31,435, by identifier

psi-UMP + H2O = pseudouridine + phosphate
Direction not assertedBalancedRhea 10944
D-glucosamine + ATP = D-glucosamine 6-phosphate + ADP + H(+)
Left to rightBalancedRhea 10948
hydroxymalonate + (E)-sinapoyl-CoA = (E)-sinapoyltartronate + CoA
Direction not assertedBalancedRhea 10952
(E)-cinnamate + NADPH + O2 + H(+) = trans-2-coumarate + NADP(+) + H2O
Direction not assertedBalancedRhea 10956
(S)-lactate = (R)-lactate
Direction not assertedBalancedRhea 10960
D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+)
Direction not assertedBalancedRhea 10964
a carboxylate + GTP + CoA = an acyl-CoA + GDP + phosphate
Direction not asserted

?

Balance undeterminable

Rhea 10968

phosphoramidate + a D-hexose + H(+) = alpha-D-hexose 1-phosphate + NH4(+)

Direction not assertedBalancedRhea 10972

quinolin-2-ol + NADH + O2 + H(+) = 5,6-dihydroquinoline-2,5,6-triol + NAD(+)

Direction not assertedBalancedRhea 10976

L-serine = D-serine

Direction not assertedBalancedRhea 10980

(S)-lactate + oxaloacetate = (S)-malate + pyruvate

Direction not assertedBalancedRhea 10984

nitrous oxide + H2O = 2 e(-) + 2 nitric oxide + 2 H(+)

Direction not assertedBalance undeterminableRhea 10988

glycolate + NADP(+) = glyoxylate + NADPH + H(+)

Direction not assertedBalancedRhea 10992

2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 10996

an N-carbamoyl-D-amino acid + H2O + 2 H(+) = a D-alpha-amino acid + NH4(+) + CO2

Direction not assertedBalance undeterminableRhea 11000

salicylate + NADH + O2 + 2 H(+) = catechol + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 11004

a 5'-end triphospho-(purine-ribonucleoside) in mRNA + H2O = a 5'-end diphospho-(purine-ribonucleoside) in mRNA + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 11008

L-tryptophanamide + H2O = L-tryptophan + NH4(+)

Direction not assertedBalancedRhea 11012

allantoate + H2O = (S)-ureidoglycolate + urea

Direction not assertedBalancedRhea 11016

1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+)

Left to rightBalancedRhea 11020

NH4(+) + ATP = phosphoramidate + ADP + 2 H(+)

Direction not assertedBalancedRhea 11024

D-mannose + ATP = D-mannose 6-phosphate + ADP + H(+)

Left to rightBalancedRhea 11028

2-[(2R)-2-chloro-2,5-dihydro-5-oxofuryl]acetate = 3-chloro-cis,cis-muconate + H(+)

Direction not assertedBalancedRhea 11032

a quaternary ammonium(out) + ATP + H2O = a quaternary ammonium(in) + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableTransportRhea 11036

D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O

Direction not assertedBalancedRhea 11040

a haloacetate + H2O = a halide anion + glycolate + H(+)

Direction not assertedBalance undeterminableRhea 11044

a 1-organyl-2-lyso-sn-glycero-3-phospholipid + a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine = a 1-organyl-2-acetyl-sn-glycero-3-phospholipid + a 1-O-alkyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 11048

4-aminobenzoate + NADH + O2 + 2 H(+) = 4-aminophenol + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 11052

4-aminobenzoate + NADPH + O2 + 2 H(+) = 4-aminophenol + CO2 + NADP(+) + H2O

Direction not assertedBalancedRhea 11056

tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate

Left to rightBalancedRhea 11060

beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate

Direction not assertedBalancedRhea 11064

(5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H2O = (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + D-glucose

Direction not assertedBalance undeterminableRhea 11068

anthranilate + NADPH + O2 + 3 H(+) = catechol + NH4(+) + CO2 + NADP(+)

Direction not assertedBalancedRhea 11072

anthranilate + NADH + O2 + 3 H(+) = catechol + NH4(+) + CO2 + NAD(+)

Direction not assertedBalancedRhea 11076

dTMP + H2O = thymidine + phosphate

Direction not assertedBalancedRhea 11080

3-dehydro-L-gulonate + H(+) = L-xylulose + CO2

Left to rightBalancedRhea 11084

trimetaphosphate + H2O = triphosphate + 2 H(+)

Direction not assertedBalancedRhea 11088

sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)

Left to rightBalancedRhea 11092

sn-glycerol 3-phosphate + NADP(+) = dihydroxyacetone phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 11096

4-hydroxyhexan-3-one = 2 propanal

Direction not assertedBalancedRhea 11100

N(alpha),N(alpha)-dimethyl-L-histidine + S-adenosyl-L-methionine = hercynine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 11104

chondroitin beta-D-glucuronate + n 3'-phosphoadenylyl sulfate = chondroitin 6'-sulfate + n adenosine 3',5'-bisphosphate + n H(+)

Left to rightBalance undeterminableRhea 11108

isochorismate + H2O = (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate

Direction not assertedBalancedRhea 11112

an alkane-alpha,omega-diamine + acetyl-CoA = an N-acetylalkane-alpha,omega-diamine + CoA + H(+)

Left to rightBalance undeterminableRhea 11116

cyanate + hydrogencarbonate + 3 H(+) = NH4(+) + 2 CO2

Direction not assertedBalancedRhea 11120

(E)-4-coumaroyl-CoA + 3 malonyl-CoA + 3 H(+) = 2',4,4',6'-tetrahydroxychalcone + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 11128

chlorophyllide a + NADP(+) = protochlorophyllide a + NADPH + H(+)

Direction not assertedBalancedRhea 11132

a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)

Left to rightBalance undeterminableRhea 11136

alpha-D-mannose 1-phosphate = D-mannose 6-phosphate

Direction not assertedBalancedRhea 11140

4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O

ReversibleBalancedRhea 11148

Page 263 of 629