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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

13,001–13,050 of 31,435, by identifier

(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H(+)
Direction not assertedBalancedRhea 10516
a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + UDP + H(+)
Direction not assertedBalance undeterminableRhea 10520
2-oxoglutarate + H(+) = succinate semialdehyde + CO2
Direction not assertedBalancedRhea 10524
dihydrosanguinarine + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxydihydrosanguinarine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 10528
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O
Direction not assertedBalancedRhea 10532
4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + sulfate + H(+)

? Direction not asserted

Balanced

Rhea 10536

7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde

Direction not assertedBalancedRhea 10540

L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O

Direction not assertedBalancedRhea 10548

D-glucose + O2 = 2-dehydro-D-glucose + H2O2

Direction not assertedBalancedRhea 10552

D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + phosphate + H(+)

Direction not assertedBalancedRhea 10556

4-hydroxy-1-pyrroline-2-carboxylate + H2O + H(+) = 2,5-dioxopentanoate + NH4(+)

Direction not assertedBalancedRhea 10560

oxaloacetate 4-methyl ester + H2O = methanol + oxaloacetate + H(+)

Direction not assertedBalancedRhea 10564

luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucuronide + UDP + H(+)

Direction not assertedBalancedRhea 10568

vinylacetyl-CoA = (2E)-butenoyl-CoA

Direction not assertedBalancedRhea 10572

N-methylethanolamine phosphate + CTP + H(+) = CDP-N-methylethanolamine + diphosphate

Direction not assertedBalancedRhea 10576

(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + L-glutamate + ATP = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 10580

4-coumaroyl-CoA + 3 malonyl-CoA + NADPH + 4 H(+) = isoliquiritigenin + 3 CO2 + NADP(+) + 4 CoA + H2O

Direction not assertedBalancedRhea 10584

a long-chain fatty acyl-[mycocerosate synthase] + 4 (R)-methylmalonyl-CoA + 8 NADPH + 12 H(+) = tetramethylated-mycocerosoyl-[mycocerosate synthase] + 4 CO2 + 8 NADP(+) + 4 CoA + 4 H2O

Direction not assertedBalance undeterminableRhea 10588

a 3',5'-unsubstituted flavanone + reduced [NADPH--hemoprotein reductase] + O2 = a 3'-hydroxy,5'-unsubstituted flavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 10592

L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)

Left to rightBalance undeterminableRhea 10596

prostaglandin H2 = prostaglandin D2

Left to rightBalancedRhea 10600

a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = phosphocholine + a 1,2-diacyl-sn-glycerol + H(+)

Left to rightBalance undeterminableRhea 10604

(E)-cinnamate + reduced [NADPH--hemoprotein reductase] + O2 = (E)-4-coumarate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 10608

N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-alpha-D-xylose = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 10612

(2R,3S)-catechin + NADP(+) + H2O = (2R,3S,4S)-leucocyanidin + NADPH + H(+)

Direction not assertedBalancedRhea 10616

(E)-cinnamaldehyde + NADP(+) + CoA = (E)-cinnamoyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 10620

tRNA(n+1) + phosphate = tRNA(n) + a ribonucleoside 5'-diphosphate

Direction not assertedBalance undeterminableRhea 10628

D-mannonate + NAD(+) = D-mannuronate + NADH + H(+)

Direction not assertedBalancedRhea 10632

D-mannonate + NADP(+) = D-mannuronate + NADPH + H(+)

Direction not assertedBalancedRhea 10636

2-oxo-2H-pyran-4,6-dicarboxylate + H2O = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(+)

Direction not assertedBalancedRhea 10644

2-hydroxycyclohexan-1-one + NADPH + O2 + H(+) = 6-hydroxyhexan-6-olide + NADP(+) + H2O

Direction not assertedBalancedRhea 10648

a long-chain fatty aldehyde + NAD(+) + H2O = a long-chain fatty acid + NADH + 2 H(+)

Left to rightBalance undeterminableRhea 10652

guanidinoacetate + S-adenosyl-L-methionine = creatine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 10656

L-seryl-[protein] = D-seryl-[protein]

Direction not assertedBalance undeterminableRhea 10660

perillyl alcohol + NAD(+) = perillyl aldehyde + NADH + H(+)

Direction not assertedBalancedRhea 10664

L-lysyl-tRNA(Lys) + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol + tRNA(Lys)

Direction not assertedBalance undeterminableRhea 10668

cyclobutadithymidine in DNA = a thymidine dimer in DNA

Direction not assertedBalance undeterminableRhea 10672

(2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H2O

Direction not assertedBalancedRhea 10676

L-proline = D-proline

Direction not assertedBalancedRhea 10680

O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate

Left to rightBalance undeterminableRhea 10684

streptomycin 6-phosphate + H2O = streptomycin + phosphate

Direction not assertedBalancedRhea 10688

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = pyrroloquinoline quinone + 2 H2O2 + 2 H2O + H(+)

Direction not assertedBalancedRhea 10692

holo-[mycocerosate synthase] + a long-chain fatty acid + ATP = a long-chain fatty acyl-[mycocerosate synthase] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 10696

limonene 1,2-epoxide + H2O = limonene-1,2-diol

Direction not assertedBalancedRhea 10700

tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate

Left to rightBalancedRhea 10704

alpha-D-glucose 1-phosphate + GTP + H(+) = GDP-D-glucose + diphosphate

Direction not assertedBalancedRhea 10708

L-phenylalanine + O2 = 2-phenylacetamide + CO2 + H2O

Direction not assertedBalancedRhea 10712

D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate

Direction not assertedBalancedRhea 10716

2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione

Direction not assertedBalancedRhea 10720

GDP-6-deoxy-alpha-D-talose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH + H(+)

Direction not assertedBalancedRhea 10724

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