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Proteins/UNIPROT:Q9H3H1
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i6A37). Mediates modification of a limited subset of tRNAs: tRNA(Ser)(AGA), tRNA(Ser)(CGA), tRNA(Ser)(UGA), as well as partial modification of the selenocysteine tRNA(Ser)(UCA). TRIT1 is therefore required for selenoprotein expression..
Function from UniProtKB (Q9H3H1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
19 statements
19 statements · 2 reference databases · Subject: TRIT1 · Sources: Hetionet, Reactome
2 reactions
MAM01706c+MAM03083cdiphosphate(3-)+MAM03060c
Catalysed by TRIT1
Reaction pageLeft to rightBalance undeterminableEC 2.5.1.75cytosol
Human-GEM MAR09523CC BY 4.0Reference data
CHEBI:74411+CHEBI:57623CHEBI:74415+diphosphate(3-)
Catalysed by TRIT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:26482CC BY 4.0Reference data
8 names
Resolves to: TRIT1