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Proteins/UNIPROT:Q9H7L9

SUDS3

Protein·UNIPROT:Q9H7L9

Open in the graph

Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes..

Function from UniProtKB (Q9H7L9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

29 statements

29 statements · 3 reference databases · Subject: SUDS3 · Sources: gene ontology, Hetionet, Reactome

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BRMS1 interacts with SUDS3ProteinHetionet hetionet:interacts:25855-64426Inferred only
CSNK2A1 interacts with SUDS3ProteinHetionet hetionet:interacts:1457-64426Inferred only
HDAC1 interacts with SUDS3ProteinHetionet hetionet:interacts:3065-64426Inferred only
SIN3A interacts with SUDS3ProteinHetionet hetionet:interacts:25942-64426Inferred only
SIN3B interacts with SUDS3ProteinHetionet hetionet:interacts:23309-64426Inferred only
SRPK1 interacts with SUDS3ProteinHetionet hetionet:interacts:64426-6732Inferred only
SUMO2 interacts with SUDS3ProteinHetionet hetionet:interacts:64426-6613Inferred only
SUDS3 participates in Chromatin modifying enzymesPathwayReactome R-HSA-3247509Inferred only
SUDS3 participates in Chromatin organizationPathwayReactome R-HSA-4839726Inferred only
SUDS3 participates in DeubiquitinationPathwayReactome R-HSA-5688426Inferred only
SUDS3 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
SUDS3 participates in Epigenetic regulation of gene expressionPathwayReactome R-HSA-212165Inferred only

Show the remaining 17

SUDS3 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
SUDS3 participates in HDACs deacetylate histonesPathwayReactome R-HSA-3214815Inferred only
SUDS3 participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
SUDS3 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
SUDS3 participates in Negative epigenetic regulation of rRNA expressionPathwayReactome R-HSA-5250941Inferred only
SUDS3 participates in NoRC negatively regulates rRNA expressionPathwayReactome R-HSA-427413Inferred only
SUDS3 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
SUDS3 participates in Potential therapeutics for SARSPathwayReactome R-HSA-9679191Inferred only
SUDS3 participates in SARS-CoV InfectionsPathwayReactome R-HSA-9679506Inferred only
SUDS3 participates in Ub-specific processing proteasesPathwayReactome R-HSA-5689880Inferred only
SUDS3 participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only
SUDS3 regulates negative regulation of cell migrationBiological processgene ontology Q9H7L9|GO:0030336Inferred only
SUDS3 regulates negative regulation of DNA-templated transcriptionBiological processgene ontology Q9H7L9|GO:0045892Inferred only
SUDS3 regulates negative regulation of stem cell population maintenanceBiological processgene ontology Q9H7L9|GO:1902455Inferred only
SUDS3 regulates negative regulation of transcription by RNA polymerase IIBiological processgene ontology Q9H7L9|GO:0000122Inferred only
SUDS3 regulates negative regulation of transforming growth factor beta receptor signaling pathwayBiological processgene ontology Q9H7L9|GO:0030512Inferred only
SUDS3 regulates positive regulation of stem cell population maintenanceBiological processgene ontology Q9H7L9|GO:1902459Inferred only

Other names

4 names

Resolves to: SUDS3

Also called: 45 kDa Sin3-associated polypeptideSAP45SDS3Suppressor of defective silencing 3 protein homolog

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