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Proteins/UNIPROT:Q9C004
Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1. Represses integrin-mediated cell spreading via inhibition of TESK1-mediated phosphorylation of cofilin..
Function from UniProtKB (Q9C004), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
43 statements
43 statements · 2 reference databases · Subject: SPRY4 · Sources: gene ontology, Hetionet
3 names
Resolves to: SPRY4