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Proteins/UNIPROT:Q9UHI7
Sodium:ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. Has retained some ancestral activity toward nucleobases such as urate, an oxidized purine. Low-affinity high-capacity sodium:urate cotransporter, may regulate serum urate levels by serving as a renal urate re-absorber..
[Isoform 2]: Inactive transporter..
Function from UniProtKB (Q9UHI7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 2 · transported by
2 compounds
2 compounds.
0 reported routes2 assembled routes
27 statements
27 statements · 6 reference databases · Subject: SLC23A1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea
5 reactions
CHEBI:17208+sodium(1+)CHEBI:17208+sodium(1+)
Transported by SLC23A2 or SLC23A1
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05021CC BY 4.0Reference data
6 names
Resolves to: SLC23A1
Human-GEM MAR06275CC BY 4.0Reference data
CHEBI:17208+ATP+water+2sodium(1+)ADP+CHEBI:17208+proton+2sodium(1+)+phosphate(3-)
Transported by SLC23A2 or SLC23A1
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR06864CC BY 4.0Reference data
L-ascorbic acid+2sodium(1+)L-ascorbic acid+2sodium(1+)
Transported by SLC23A2 or SLC23A1
Reaction pageLeft to rightBalanced
Rhea RHEA:69883CC BY 4.0Reference data
urate+2sodium(1+)urate+2sodium(1+)
Transported by SLC23A1
Reaction pageLeft to rightBalanced
Rhea RHEA:76339CC BY 4.0Reference data