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Proteins/UNIPROT:Q9HAJ7
[Isoform 1]: Functions as a transcription repressor, probably via its interaction with histone deacetylase complexes. Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus. Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA. Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import..
[Isoform 2]: Functions as a transcription repressor; isoform 2 has lower transcription repressor activity than isoform 1 and isoform 3..
[Isoform 3]: Functions as a transcription repressor; its activity is marginally lower than that of isoform 1..
Function from UniProtKB (Q9HAJ7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
38 statements
38 statements · 3 reference databases · Subject: SAP30L · Sources: gene ontology, Hetionet, Reactome
4 names
Resolves to: SAP30L