Proteins/UNIPROT:Q92766

RREB1

ProteinUNIPROT:Q92766

Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1. Promotes brown adipocyte differentiation (By similarity). May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression..

Function from UniProtKB (Q92766), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

22q11.2 deletion syndrome has a germline basis in RREB1DiseaseGenCC HGNC:10449|MONDO:0018923Inferred only
RASopathy has a germline basis in RREB1DiseaseGenCC HGNC:10449|MONDO:0021060Inferred only

Statements

19 statements

19 statements · 2 reference databases · Subject: RREB1 · Sources: gene ontology, Hetionet

Order

RREB1 covaries with LRRC75BProteinHetionet hetionet:covaries:388886-6239Inferred only
RREB1 covaries with ZNF500ProteinHetionet hetionet:covaries:26048-6239Inferred only
NEUROD1 interacts with RREB1ProteinHetionet hetionet:interacts:4760-6239Inferred only
RREB1 regulates negative regulation of transcription by RNA polymerase IIBiological processgene ontology Q92766|GO:0000122Inferred only
RREB1 regulates positive regulation of brown fat cell differentiationBiological processgene ontology Q92766|GO:0090336Inferred only
RREB1 regulates positive regulation of DNA-templated transcriptionBiological processgene ontology Q92766|GO:0045893Inferred only
RREB1 regulates positive regulation of epithelial cell migrationBiological processgene ontology Q92766|GO:0010634Inferred only
RREB1 regulates positive regulation of lamellipodium morphogenesisBiological processgene ontology Q92766|GO:2000394Inferred only
RREB1 regulates positive regulation of mammary gland epithelial cell proliferationBiological processgene ontology Q92766|GO:0033601Inferred only
RREB1 regulates positive regulation of substrate adhesion-dependent cell spreadingBiological processgene ontology Q92766|GO:1900026Inferred only
RREB1 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q92766|GO:0045944Inferred only
RREB1 regulates positive regulation of wound healing, spreading of epidermal cellsBiological processgene ontology Q92766|GO:1903691Inferred only

Show the remaining 7

RREB1 regulates regulation of DNA-templated transcriptionBiological processgene ontology Q92766|GO:0006355Inferred only
RREB1 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q92766|GO:0006357Inferred only
MTHFD2 increases the expression of RREB1ProteinHetionet hetionet:regulates:10797-6239Inferred only
MTOR increases the expression of RREB1ProteinHetionet hetionet:regulates:2475-6239Inferred only
NPRL2 increases the expression of RREB1ProteinHetionet hetionet:regulates:10641-6239Inferred only
RTCA decreases the expression of RREB1ProteinHetionet hetionet:regulates:8634-6239Inferred only
TIMP1 increases the expression of RREB1ProteinHetionet hetionet:regulates:7076-6239Inferred only

Other names

6 names

Resolves to: RREB1

Also called: FINBFinger protein in nuclear bodiesRaf-responsive zinc finger protein LZ321RREB-1Zep-1Zinc finger motif enhancer-binding protein 1

← Every protein Find it in the graph →