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Reference

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q8IZ41

RASEF

Protein·UNIPROT:Q8IZ41

Open in the graph

[Isoform 1]: Rab GTPase that acts as a dynein adapter protein, thereby activating dynein-mediated transport and dynein-dynactin motility on microtubules. RASEF-mediated dynein motility is Ca(2+)-independent. Also regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells (By similarity)..

Function from UniProtKB (Q8IZ41), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

3 statements

3 statements · 2 reference databases · Subject: RASEF · Sources: Hetionet, UniProt

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CPXCR1 covaries with RASEFProteinHetionet hetionet:covaries:158158-53336Inferred only
UBC interacts with RASEFProteinHetionet hetionet:interacts:158158-7316Inferred only
RASEF requires the cofactor magnesium(2+)CompoundUniProt Q8IZ41Inferred only

Reactions

1 reaction

GTP+waterGDP+hydrogenphosphate+hydron
Catalysed by IRGM or RAB19 or TUBAL3 or GTPBP1 or RAB27B or RHOD or DNM1L or MRAS or RAB29 or OPA1 or EIF5B or ENTPD3 and 183 more alternatives
Reaction page

Other names

2 names

Resolves to: RASEF

Also called: RAB45Ras-related protein Rab-45

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Balanced

Rhea RHEA:19669CC BY 4.0Reference data