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Reference

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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q9UNT1

RABL2B

Protein·UNIPROT:Q9UNT1

Open in the graph

Small GTPase required for ciliation. Activated in a guanine nucleotide exchange factor (GEF)-independent manner via its intrinsic GDP for GTP nucleotide exchange ability. Involved in ciliary assembly by binding the intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia..

Function from UniProtKB (Q9UNT1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

5 statements

5 statements · 3 reference databases · Subject: RABL2B · Sources: Hetionet, UniProt, WikiPathways

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RABL2B interacts with CEP19ProteinHetionet hetionet:interacts:11158-84984Inferred only
UBC interacts with RABL2BProteinHetionet hetionet:interacts:11158-7316Inferred only
RABL2B participates in 3q29 copy number variation syndromePathwayWikiPathways WP4906Inferred only
RABL2B participates in Genes related to primary cilium development based on CRISPR PathwayWikiPathways WP4536Inferred only
RABL2B requires the cofactor magnesium(2+)CompoundUniProt Q9UNT1Inferred only

Reactions

1 reaction

GTP+waterGDP+hydrogenphosphate+hydron
Catalysed by IRGM or RAB19 or TUBAL3 or GTPBP1 or RAB27B or RHOD or DNM1L or MRAS or RAB29 or OPA1 or EIF5B or ENTPD3 and 183 more alternatives
Reaction page

Other names

1 name

Resolves to: RABL2B

Also called: Rab-like protein 2B

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Balanced

Rhea RHEA:19669CC BY 4.0Reference data