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Proteins/UNIPROT:P51157
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB28 is required for shedding and phagocytosis of cone cell outer segments (OS) discs in the retina (By similarity). Also participates in nuclear factor kappa-B p65/RELA nuclear transport in endothelial cells (By similarity)..
Function from UniProtKB (P51157), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
3 statements
3 statements · 2 reference databases · Subject: RAB28 · Sources: Hetionet, UniProt
1 reaction
1 name
Resolves to: RAB28
Rhea RHEA:19669CC BY 4.0Reference data