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Proteins/UNIPROT:Q67FW5
Glycosyltransferase that specifically catalyzes galactosylation of cytoplasmic tRNA(Tyr) modified with queuosine at position 34 (queuosine(34)). Galactosylates the cyclopentene hydroxyl group of queuosine(34) in tRNA(Tyr) to form galactosyl-queuosine(34). Mannosylation of queuosine(34) in tRNA(Tyr) is required to slow-down elongation at cognate codons UAC and suppress stop codon readthrough, thereby regulating protein translation..
Function from UniProtKB (Q67FW5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
41 statements
41 statements · 5 reference databases · Subject: QTGAL · Sources: gene ontology, Hetionet, Human Protein Atlas, Reactome, Rhea
1 reaction
CHEBI:194431+UDP-alpha-D-galactoseCHEBI:228254+UDP+hydron
Catalysed by QTGAL
Reaction pageLeft to rightBalanced
Rhea RHEA:78231CC BY 4.0Reference data
11 names
Resolves to: QTGAL