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Proteins/UNIPROT:Q8N0Z8

PUSL1

Protein·UNIPROT:Q8N0Z8

Open in the graph

Pseudouridylate synthase that catalyzes the conversion of uridine to pseudouridine in mitochondrial tRNAs. Acts on position 38/39/40 in the anticodon stem of mitochondrial tRNAs..

Function from UniProtKB (Q8N0Z8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

5 statements

5 statements · 2 reference databases · Subject: PUSL1 · Sources: Hetionet, WikiPathways

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ITGAE covaries with PUSL1ProteinHetionet hetionet:covaries:126789-3682Inferred only
APP interacts with PUSL1ProteinHetionet hetionet:interacts:126789-351Inferred only
MRPL58 interacts with PUSL1ProteinHetionet hetionet:interacts:126789-3396Inferred only
UBC interacts with PUSL1ProteinHetionet hetionet:interacts:126789-7316Inferred only
PUSL1 participates in 1p36 copy number variation syndromePathwayWikiPathways WP5345Inferred only

Reactions

1 reaction

CHEBI:65315CHEBI:65314
Catalysed by PUSL1 or PUS1
Reaction pageLeft to rightBalanced
Rhea RHEA:22376CC BY 4.0Reference data

Other names

3 names

Resolves to: PUSL1

Also called: tRNA pseudouridine (38/39/40) synthase-like 1tRNA pseudouridylate synthase-like 1tRNA-uridine isomerase-like 1

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