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Proteins/UNIPROT:Q6P2P2

PRMT9

Protein·UNIPROT:Q6P2P2Protein arginine N-methyltransferase 9

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Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA..

Function from UniProtKB (Q6P2P2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

complex neurodevelopmental disorder has a germline basis in PRMT9DiseaseGenCC HGNC:25099|MONDO:0100038Inferred only

Statements

7 statements

7 statements · 2 reference databases · Subject: PRMT9 · Sources: gene ontology, Hetionet

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PRMT9 covaries with CCDC15ProteinHetionet hetionet:covaries:80071-90826Inferred only
PRMT9 covaries with LHFPL4ProteinHetionet hetionet:covaries:375323-90826Inferred only
NLRC4 covaries with PRMT9ProteinHetionet hetionet:covaries:58484-90826Inferred only
PRMT9 covaries with UGGT2ProteinHetionet hetionet:covaries:55757-90826Inferred only
PRMT9 covaries with ZNF514ProteinHetionet hetionet:covaries:84874-90826Inferred only
UBC interacts with PRMT9ProteinHetionet hetionet:interacts:7316-90826Inferred only
PRMT9 regulates regulation of DNA-templated transcriptionBiological processgene ontology Q6P2P2|GO:0006355Inferred only

Reactions

1 reaction

L-arginyl-[protein]+2S-adenosyl-L-methionineN(omega),N(omega)'-dimethyl-L-arginyl-[protein]+2S-adenosyl-L-homocysteine+2hydron
Catalysed by PRMT5 or PRMT9 or NDUFAF7
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:48108CC BY 4.0Reference data

Other names

3 names

Resolves to: PRMT9

Also called: arginine N-methyltransferase 10PRMT10Protein arginine N-methyltransferase 10

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