Proteins/UNIPROT:Q8IXA5

SPACA3

ProteinUNIPROT:Q8IXA5

Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro..

Function from UniProtKB (Q8IXA5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: SPACA3 · Sources: gene ontology, Hetionet

Order

BCL2 covaries with SPACA3ProteinHetionet hetionet:covaries:124912-596Inferred only
ERGIC3 covaries with SPACA3ProteinHetionet hetionet:covaries:124912-51614Inferred only
FCHSD1 covaries with SPACA3ProteinHetionet hetionet:covaries:124912-89848Inferred only
POU2F3 covaries with SPACA3ProteinHetionet hetionet:covaries:124912-25833Inferred only
SPACA3 covaries with SLIT1ProteinHetionet hetionet:covaries:124912-6585Inferred only
TRIM3 covaries with SPACA3ProteinHetionet hetionet:covaries:10612-124912Inferred only
UBC interacts with SPACA3ProteinHetionet hetionet:interacts:124912-7316Inferred only
SPACA3 regulates positive regulation of macrophage activationBiological processgene ontology Q8IXA5|GO:0043032Inferred only
SPACA3 regulates positive regulation of phagocytosisBiological processgene ontology Q8IXA5|GO:0050766Inferred only

Other names

11 names

Resolves to: SPACA3

Also called: Cancer/testis antigen 54CT54LYC3Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17Lysozyme-like protein 3LYZL3SLLP1Sperm lysozyme-like protein 1Sperm protein reactive with antisperm antibodiesSperm protein reactive with ASASPRASA

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