Loading the page.
Proteins/UNIPROT:Q8WZ55
Regulatory subunit of anion-selective CLCNKA:BSND and CLCNKB:BSND heteromeric channels involved in basolateral chloride conductance along the nephron to achieve urine concentration and maintain systemic acid-base homeostasis, and in the stria vascularis of the inner ear to establish the endocochlear potential necessary for normal hearing. Most likely acts as a chaperone that allosterically regulates proper sorting of CLCNKA:BSND and CLCNKB:BSND channels at the basolateral plasma membrane domain and functional switch to ion conducting state. Mediates constitutive opening of channel common gates..
Function from UniProtKB (Q8WZ55), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
9 statements
9 statements · 2 reference databases · Subject: BSND · Sources: Hetionet, Reactome
2 names
Resolves to: BSND