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Proteins/UNIPROT:Q8TBF5
Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM..
Function from UniProtKB (Q8TBF5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
9 statements
9 statements · 3 reference databases · Subject: PIGX · Sources: Hetionet, Reactome, WikiPathways
1 reaction
MAM01734r+MAM01964rMAM01733r+proton+MAM02483r
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-endoplasmic reticulum
Human-GEM MAR08383CC BY 4.0Reference data
2 names
Resolves to: PIGX