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Proteins/UNIPROT:A8MW92

PHF20L1

Protein·UNIPROT:A8MW92

Open in the graph

Is a negative regulator of proteasomal degradation of a set of methylated proteins, including DNMT1 and SOX2. Involved in the maintainance of embryonic stem cells pluripotency, through the regulation of SOX2 levels (By similarity)..

Function from UniProtKB (A8MW92), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

51 statements

51 statements · 3 reference databases · Subject: PHF20L1 · Sources: gene ontology, Hetionet, Reactome

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PHF20L1 covaries with ALKBH7ProteinHetionet hetionet:covaries:51105-84266Inferred only
PNISR covaries with PHF20L1ProteinHetionet hetionet:covaries:25957-51105Inferred only
QTMAN covaries with PHF20L1ProteinHetionet hetionet:covaries:51105-79712Inferred only
APP interacts with PHF20L1ProteinHetionet hetionet:interacts:351-51105Inferred only
CASP10 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-843Inferred only
ELAVL4 interacts with PHF20L1ProteinHetionet hetionet:interacts:1996-51105Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8353Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8356Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8968Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8351Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8352Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8357Inferred only

Show the remaining 39

H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8355Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8358Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8350Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8354Inferred only
PHF20L1 interacts with H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16ProteinHetionet hetionet:interacts:121504-51105Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8360Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8359Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8365Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8363Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8367Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8362Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8294Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8361Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8370Inferred only
PHF20L1 interacts with H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16ProteinHetionet hetionet:interacts:51105-554313Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8366Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8364Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-8368Inferred only
PHF20L1 interacts with LYARProteinHetionet hetionet:interacts:51105-55646Inferred only
UBC interacts with PHF20L1ProteinHetionet hetionet:interacts:51105-7316Inferred only
WWP1 interacts with PHF20L1ProteinHetionet hetionet:interacts:11059-51105Inferred only
PHF20L1 participates in Epigenetic regulation by WDR5-containing histone modifying complexesPathwayReactome R-HSA-9917777Inferred only
PHF20L1 participates in Epigenetic regulation of gene expressionPathwayReactome R-HSA-212165Inferred only
PHF20L1 participates in Formation of WDR5-containing histone-modifying complexesPathwayReactome R-HSA-9772755Inferred only
PHF20L1 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
PHF20L1 regulates negative regulation of proteasomal ubiquitin-dependent protein catabolic processBiological processgene ontology A8MW92|GO:0032435Inferred only
PHF20L1 regulates negative regulation of protein catabolic processBiological processgene ontology A8MW92|GO:0042177Inferred only
PHF20L1 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology A8MW92|GO:0006357Inferred only
PHF20L1 decreases the expression of B4GAT1ProteinHetionet hetionet:regulates:51105-11041Inferred only
PHF20L1 decreases the expression of C2CD5ProteinHetionet hetionet:regulates:51105-9847Inferred only
PHF20L1 decreases the expression of CNDP2ProteinHetionet hetionet:regulates:51105-55748Inferred only
PHF20L1 decreases the expression of CRKLProteinHetionet hetionet:regulates:51105-1399Inferred only
PHF20L1 decreases the expression of EEF1A2ProteinHetionet hetionet:regulates:51105-1917Inferred only
PHF20L1 increases the expression of EPCAMProteinHetionet hetionet:regulates:51105-4072Inferred only
PHF20L1 decreases the expression of FOXO4ProteinHetionet hetionet:regulates:51105-4303Inferred only
PHF20L1 decreases the expression of PGM1ProteinHetionet hetionet:regulates:51105-5236Inferred only
PHF20L1 increases the expression of SERPINA1ProteinHetionet hetionet:regulates:51105-5265Inferred only
PHF20L1 decreases the expression of TCN1ProteinHetionet hetionet:regulates:51105-6947Inferred only
PHF20L1 increases the expression of TFProteinHetionet hetionet:regulates:51105-7018Inferred only

Other names

1 name

Resolves to: PHF20L1

Also called: PHD finger protein 20-like protein 1

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