Proteins/UNIPROT:P56589

PEX3

ProteinUNIPROT:P56589

Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes..

Function from UniProtKB (P56589), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

4 rows

peroxisome biogenesis disorder has a germline basis in PEX3DiseaseGenCC HGNC:8858|MONDO:0019234Inferred only
peroxisome biogenesis disorder 10A (Zellweger) has a germline basis in PEX3DiseaseGenCC HGNC:8858|MONDO:0013948Inferred only
peroxisome biogenesis disorder 10B has a germline basis in PEX3DiseaseGenCC HGNC:8858|MONDO:0054549Inferred only
Zellweger spectrum disorders has a germline basis in PEX3DiseaseGenCC HGNC:8858|MONDO:0019609Inferred only

Statements

25 statements

25 statements · 3 reference databases · Subject: PEX3 · Sources: Hetionet, Reactome, WikiPathways

Order

PEX3 covaries with ATF5ProteinHetionet hetionet:covaries:22809-8504Inferred only
PEX3 covaries with CKBProteinHetionet hetionet:covaries:1152-8504Inferred only
PEX3 covaries with HNRNPA0ProteinHetionet hetionet:covaries:10949-8504Inferred only
HOXC12 covaries with PEX3ProteinHetionet hetionet:covaries:3228-8504Inferred only
MANSC4 covaries with PEX3ProteinHetionet hetionet:covaries:100287284-8504Inferred only
PEX3 covaries with NTF4ProteinHetionet hetionet:covaries:4909-8504Inferred only
PEX3 covaries with PRKAA1ProteinHetionet hetionet:covaries:5562-8504Inferred only
PEX3 covaries with RBX1ProteinHetionet hetionet:covaries:8504-9978Inferred only
PEX3 covaries with RFNGProteinHetionet hetionet:covaries:5986-8504Inferred only
PEX3 covaries with THOP1ProteinHetionet hetionet:covaries:7064-8504Inferred only
PEX3 covaries with TMEM238ProteinHetionet hetionet:covaries:388564-8504Inferred only
PEX19 interacts with PEX3ProteinHetionet hetionet:interacts:5824-8504Inferred only

Show the remaining 13

UBC interacts with PEX3ProteinHetionet hetionet:interacts:7316-8504Inferred only
PEX3 participates in 11p11 2 copy number variation syndrome PathwayWikiPathways WP5348Inferred only
PEX3 participates in ABC transporters in lipid homeostasisPathwayReactome R-HSA-1369062Inferred only
PEX3 participates in ABC-family protein mediated transportPathwayReactome R-HSA-382556Inferred only
PEX3 participates in Class I peroxisomal membrane protein importPathwayReactome R-HSA-9603798Inferred only
PEX3 participates in Ether lipid biosynthesisPathwayWikiPathways WP5275Inferred only
PEX3 participates in Protein localizationPathwayReactome R-HSA-9609507Inferred only
PEX3 participates in Transport of small moleculesPathwayReactome R-HSA-382551Inferred only
ERG increases the expression of PEX3ProteinHetionet hetionet:regulates:2078-8504Inferred only
PCMT1 decreases the expression of PEX3ProteinHetionet hetionet:regulates:5110-8504Inferred only
PEPD decreases the expression of PEX3ProteinHetionet hetionet:regulates:5184-8504Inferred only
RBM15 decreases the expression of PEX3ProteinHetionet hetionet:regulates:64783-8504Inferred only
YKT6 increases the expression of PEX3ProteinHetionet hetionet:regulates:10652-8504Inferred only

Other names

2 names

Resolves to: PEX3

Also called: Peroxin-3Peroxisomal assembly protein PEX3

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