Proteins/UNIPROT:Q9UPQ7

PDZRN3

ProteinUNIPROT:Q9UPQ7

E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation..

Function from UniProtKB (Q9UPQ7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

9 statements

9 statements · 1 reference database · Subject: PDZRN3 · Sources: Hetionet

Order

PDZRN3 covaries with MESP2ProteinHetionet hetionet:covaries:145873-23024Inferred only
SLC29A4 covaries with PDZRN3ProteinHetionet hetionet:covaries:222962-23024Inferred only
PDZRN3 covaries with ZNF536ProteinHetionet hetionet:covaries:23024-9745Inferred only
BMPR2 interacts with PDZRN3ProteinHetionet hetionet:interacts:23024-659Inferred only
EFNB2 interacts with PDZRN3ProteinHetionet hetionet:interacts:1948-23024Inferred only
PDZRN3 interacts with LNX1ProteinHetionet hetionet:interacts:23024-84708Inferred only
PDZRN3 interacts with LNX2ProteinHetionet hetionet:interacts:222484-23024Inferred only
MUSK interacts with PDZRN3ProteinHetionet hetionet:interacts:23024-4593Inferred only
UBE2D2 interacts with PDZRN3ProteinHetionet hetionet:interacts:23024-7322Inferred only

Other names

9 names

Resolves to: PDZRN3

Also called: KIAA1095Ligand of Numb protein X 3LNX3PDZ domain-containing RING finger protein 3Protein SEMACAP3RING-type E3 ubiquitin transferase PDZRN3SEMACAP3Semaphorin cytoplasmic domain-associated protein 3SEMCAP3

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