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Proteins/UNIPROT:Q969R2
Mediates the bidirectional lipid exchange between intracellular compartments and the plasma membrane, delivering cholesterol to the plasma membrane while transferring PI(4,5)P(2) to internal organelles, thereby modulating membrane lipid composition and associated signaling pathways. Binds 7-ketocholesterol. Acts during spermatid development where its function is required prior to the removal of cytoplasm from the sperm head (By similarity)..
Function from UniProtKB (Q969R2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
5 statements
5 statements · 3 reference databases · Subject: OSBP2 · Sources: Bgee, Hetionet, Rhea
1 reaction
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)+cholesterola 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)+cholesterol
Transported by OSBP2 or OSBPL2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:84879CC BY 4.0Reference data
7 names
Resolves to: OSBP2