Proteins/UNIPROT:P19652

ORM2

ProteinUNIPROT:P19652

Functions as a transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction..

Function from UniProtKB (P19652), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

15 statements

15 statements · 4 reference databases · Subject: ORM2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

ORM2 interacts with CYP39A1ProteinHetionet hetionet:interacts:5005-51302Inferred only
ORM2 interacts with PRDX6ProteinHetionet hetionet:interacts:5005-9588Inferred only
ORM2 interacts with STK3ProteinHetionet hetionet:interacts:5005-6788Inferred only
ORM2 participates in HemostasisPathwayReactome R-HSA-109582Inferred only
ORM2 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
ORM2 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
ORM2 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
ORM2 participates in Platelet activation, signaling and aggregationPathwayReactome R-HSA-76002Inferred only
ORM2 participates in Platelet degranulationPathwayReactome R-HSA-114608Inferred only
ORM2 participates in Response to elevated platelet cytosolic Ca2+PathwayReactome R-HSA-76005Inferred only
ORM2 participates in Vitamin D receptor pathwayPathwayWikiPathways WP2877Inferred only
ORM2 regulates positive regulation of interleukin-1 beta productionBiological processgene ontology P19652|GO:0032731Inferred only

Show the remaining 3

ORM2 regulates positive regulation of interleukin-1 productionBiological processgene ontology P19652|GO:0032732Inferred only
ORM2 regulates positive regulation of tumor necrosis factor productionBiological processgene ontology P19652|GO:0032760Inferred only
ORM2 regulates regulation of immune system processBiological processgene ontology P19652|GO:0002682Inferred only

Other names

4 names

Resolves to: ORM2

Also called: AGP 2AGP2OMD 2Orosomucoid-2

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