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Proteins/UNIPROT:O43847
Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs. Is a critical activator of BACE1- and ADAM17-mediated pro-neuregulin ectodomain shedding, involved in the positive regulation of axonal maturation and myelination. Required for proper functioning of 2-oxoglutarate dehydrogenase (OGDH) (By similarity)..
Function from UniProtKB (O43847), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
43 statements
43 statements · 3 reference databases · Subject: NRDC · Sources: gene ontology, Hetionet, UniProt
5 names
Resolves to: NRDC