Proteins/UNIPROT:P98088

MUC5AC

ProteinUNIPROT:P98088

Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD)..

Function from UniProtKB (P98088), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

24 statements

24 statements · 3 reference databases · Subject: MUC5AC · Sources: Hetionet, Reactome, WikiPathways

Order

MUC5AC interacts with GALNT12ProteinHetionet hetionet:interacts:4586-79695Inferred only
MUC5AC interacts with GALNT14ProteinHetionet hetionet:interacts:4586-79623Inferred only
MUC5AC participates in C-type lectin receptors (CLRs)PathwayReactome R-HSA-5621481Inferred only
MUC5AC participates in Dectin-2 familyPathwayReactome R-HSA-5621480Inferred only
MUC5AC participates in Defective C1GALT1C1 causes TNPSPathwayReactome R-HSA-5083632Inferred only
MUC5AC participates in Defective GALNT12 causes CRCS1PathwayReactome R-HSA-5083636Inferred only
MUC5AC participates in Defective GALNT3 causes HFTCPathwayReactome R-HSA-5083625Inferred only
MUC5AC participates in DiseasePathwayReactome R-HSA-1643685Inferred only
MUC5AC participates in Diseases associated with O-glycosylation of proteinsPathwayReactome R-HSA-3906995Inferred only
MUC5AC participates in Diseases of glycosylationPathwayReactome R-HSA-3781865Inferred only
MUC5AC participates in Diseases of metabolismPathwayReactome R-HSA-5668914Inferred only
MUC5AC participates in IL19 signalingPathwayWikiPathways WP5422Inferred only

Show the remaining 12

MUC5AC participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
MUC5AC participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
MUC5AC participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
MUC5AC participates in O-linked glycosylationPathwayReactome R-HSA-5173105Inferred only
MUC5AC participates in O-linked glycosylation of mucinsPathwayReactome R-HSA-913709Inferred only
MUC5AC participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
MUC5AC participates in Termination of O-glycan biosynthesisPathwayReactome R-HSA-977068Inferred only
DNMT1 increases the expression of MUC5ACProteinHetionet hetionet:regulates:1786-4586Inferred only
GALE decreases the expression of MUC5ACProteinHetionet hetionet:regulates:2582-4586Inferred only
PCBD1 decreases the expression of MUC5ACProteinHetionet hetionet:regulates:5092-4586Inferred only
RAD9A decreases the expression of MUC5ACProteinHetionet hetionet:regulates:5883-4586Inferred only
TIMP1 decreases the expression of MUC5ACProteinHetionet hetionet:regulates:7076-4586Inferred only

Other names

7 names

Resolves to: MUC5AC

Also called: Gastric mucinMajor airway glycoproteinMUC-5ACMUC5Mucin-5 subtype AC, tracheobronchialTBMTracheobronchial mucin

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