Proteins/UNIPROT:Q9H3U5

MFSD1

ProteinUNIPROT:Q9H3U5

Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis (By similarity)..

Function from UniProtKB (Q9H3U5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 1 reference database · Subject: MFSD1 · Sources: Hetionet

Order

MFSD1 covaries with SLCO1B3ProteinHetionet hetionet:covaries:28234-64747Inferred only
MFSD1 covaries with TNFSF9ProteinHetionet hetionet:covaries:64747-8744Inferred only
MFSD1 covaries with ZNF554ProteinHetionet hetionet:covaries:115196-64747Inferred only
C2CD2 increases the expression of MFSD1ProteinHetionet hetionet:regulates:25966-64747Inferred only
CREBL2 increases the expression of MFSD1ProteinHetionet hetionet:regulates:1389-64747Inferred only
HEY1 increases the expression of MFSD1ProteinHetionet hetionet:regulates:23462-64747Inferred only
HEY2 increases the expression of MFSD1ProteinHetionet hetionet:regulates:23493-64747Inferred only
JUN increases the expression of MFSD1ProteinHetionet hetionet:regulates:3725-64747Inferred only
MLST8 increases the expression of MFSD1ProteinHetionet hetionet:regulates:64223-64747Inferred only
POLR2I increases the expression of MFSD1ProteinHetionet hetionet:regulates:5438-64747Inferred only
PPP3R1 increases the expression of MFSD1ProteinHetionet hetionet:regulates:5534-64747Inferred only
SLC25A14 increases the expression of MFSD1ProteinHetionet hetionet:regulates:9016-64747Inferred only

Reactions

13 reactions

CHEBI:229968CHEBI:229968
Transported by MFSD1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79367CC BY 4.0Reference data
CHEBI:84315CHEBI:84315
Transported by MFSD1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79371CC BY 4.0Reference data
CHEBI:229967CHEBI:229967
Transported by MFSD1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79375

Other names

4 names

Resolves to: MFSD1

Also called: Major facilitator superfamily domain-containing protein 1SMAP-4SMAP4Smooth muscle cell-associated protein 4

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