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Proteins/UNIPROT:Q68EN5
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Also able to remove the C-terminal phenylalanine residue of alpha-tubulin TUBA8. Recognizes adjacent tubulin dimers along the same protofilament..
Function from UniProtKB (Q68EN5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
19 statements
19 statements · 3 reference databases · Subject: MATCAP1 · Sources: Bgee, Hetionet, UniProt
2 reactions
C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin]+waterC-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin]+L-tyrosine
Catalysed by MATCAP1 or VASH1 or VASH2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:57444CC BY 4.0Reference data
C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-phenylalanyl-[tubulin]+waterC-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin]+L-phenylalanine
Catalysed by MATCAP1
3 names
Resolves to: MATCAP1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:72663CC BY 4.0Reference data