Proteins/UNIPROT:P08519

LPA

ProteinUNIPROT:P08519

Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330..

Function from UniProtKB (P08519), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

16 statements

16 statements · 3 reference databases · Subject: LPA · Sources: Hetionet, Reactome, WikiPathways

Order

APOH interacts with LPAProteinHetionet hetionet:interacts:350-4018Inferred only
CANX interacts with LPAProteinHetionet hetionet:interacts:4018-821Inferred only
CELA1 interacts with LPAProteinHetionet hetionet:interacts:1990-4018Inferred only
ELANE interacts with LPAProteinHetionet hetionet:interacts:1991-4018Inferred only
LPA interacts with FBLN5ProteinHetionet hetionet:interacts:10516-4018Inferred only
FGB interacts with LPAProteinHetionet hetionet:interacts:2244-4018Inferred only
FN1 interacts with LPAProteinHetionet hetionet:interacts:2335-4018Inferred only
LPA interacts with LRP2ProteinHetionet hetionet:interacts:4018-4036Inferred only
LPA interacts with MMP12ProteinHetionet hetionet:interacts:4018-4321Inferred only
LPA participates in Cholesterol metabolismPathwayWikiPathways WP5304Inferred only
LPA participates in Fatty acid and lipoprotein transport in hepatocytesPathwayWikiPathways WP5323Inferred only
LPA participates in Fibrotic response of trabecular meshwork cells to TGFB3 and ENPP2 in aqueous humorPathwayWikiPathways WP5545Inferred only

Show the remaining 4

LPA participates in LDL remodelingPathwayReactome R-HSA-8964041Inferred only
LPA participates in Plasma lipoprotein assembly, remodeling, and clearancePathwayReactome R-HSA-174824Inferred only
LPA participates in Plasma lipoprotein remodelingPathwayReactome R-HSA-8963899Inferred only
LPA participates in Transport of small moleculesPathwayReactome R-HSA-382551Inferred only

Other names

3 names

Resolves to: LPA

Also called: aApo(a)Lp(a)

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