Proteins/UNIPROT:O60333

KIF1B

ProteinUNIPROT:O60333

Has a plus-end-directed microtubule motor activity and functions as a motor for transport of vesicles and organelles along microtubules..

[Isoform 2]: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde synaptic vesicle transport along axonal microtubules from the cell body to the presynapse in neuronal cells (By similarity). Functions as a downstream effector in a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells..

[Isoform 3]: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde transport of mitochondria..

Function from UniProtKB (O60333), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

3 rows

Charcot-Marie-Tooth disease type 2A1 has a germline basis in KIF1BDiseaseGenCC HGNC:16636|MONDO:0007308Inferred only
hereditary pheochromocytoma-paraganglioma has a germline basis in KIF1BDiseaseGenCC HGNC:16636|MONDO:0017366Inferred only
pheochromocytoma has a germline basis in KIF1BDiseaseGenCC HGNC:16636|MONDO:0008233Inferred only

Statements

25 statements

25 statements · 3 reference databases · Subject: KIF1B · Sources: Hetionet, Reactome, WikiPathways

Order

ARHGAP1 interacts with KIF1BProteinHetionet hetionet:interacts:23095-392Inferred only
CHP1 interacts with KIF1BProteinHetionet hetionet:interacts:11261-23095Inferred only
KIF1B interacts with CPEB1ProteinHetionet hetionet:interacts:23095-64506Inferred only
DLG1 interacts with KIF1BProteinHetionet hetionet:interacts:1739-23095Inferred only
DLG2 interacts with KIF1BProteinHetionet hetionet:interacts:1740-23095Inferred only
DLG3 interacts with KIF1BProteinHetionet hetionet:interacts:1741-23095Inferred only
DLG4 interacts with KIF1BProteinHetionet hetionet:interacts:1742-23095Inferred only
EEF1A1 interacts with KIF1BProteinHetionet hetionet:interacts:1915-23095Inferred only
GIPC1 interacts with KIF1BProteinHetionet hetionet:interacts:10755-23095Inferred only
MAGI1 interacts with KIF1BProteinHetionet hetionet:interacts:23095-9223Inferred only
SNTA1 interacts with KIF1BProteinHetionet hetionet:interacts:23095-6640Inferred only
KIF1B interacts with STARD13ProteinHetionet hetionet:interacts:23095-90627Inferred only

Show the remaining 13

KIF1B participates in COPI-dependent Golgi-to-ER retrograde trafficPathwayReactome R-HSA-6811434Inferred only
KIF1B participates in Effects of MFN2 mutationPathwayWikiPathways WP5443Inferred only
KIF1B participates in Factors involved in megakaryocyte development and platelet productionPathwayReactome R-HSA-983231Inferred only
KIF1B participates in Golgi-to-ER retrograde transportPathwayReactome R-HSA-8856688Inferred only
KIF1B participates in HemostasisPathwayReactome R-HSA-109582Inferred only
KIF1B participates in Intra-Golgi and retrograde Golgi-to-ER trafficPathwayReactome R-HSA-6811442Inferred only
KIF1B participates in Intracellular trafficking proteins involved in CMT neuropathyPathwayWikiPathways WP4856Inferred only
KIF1B participates in KinesinsPathwayReactome R-HSA-983189Inferred only
KIF1B participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
KIF1B participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
GNPDA1 increases the expression of KIF1BProteinHetionet hetionet:regulates:10007-23095Inferred only
GSTZ1 increases the expression of KIF1BProteinHetionet hetionet:regulates:2954-23095Inferred only
HK1 increases the expression of KIF1BProteinHetionet hetionet:regulates:3098-23095Inferred only

Other names

3 names

Resolves to: KIF1B

Also called: KIAA0591KIAA1448Klp

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