Proteins/UNIPROT:Q8NI77

KIF18A

ProteinUNIPROT:Q8NI77

Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression..

Function from UniProtKB (Q8NI77), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

40 statements

40 statements · 2 reference databases · Subject: KIF18A · Sources: Hetionet, Reactome

Order

MIS18BP1 covaries with KIF18AProteinHetionet hetionet:covaries:55320-81930Inferred only
PPP1CA interacts with KIF18AProteinHetionet hetionet:interacts:5499-81930Inferred only
UBC interacts with KIF18AProteinHetionet hetionet:interacts:7316-81930Inferred only
KIF18A participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
KIF18A participates in Affinity selection of immunoglobulinsPathwayReactome R-HSA-9938027Inferred only
KIF18A participates in Amplification of signal from unattached kinetochores via a MAD2 inhibitory signalPathwayReactome R-HSA-141444Inferred only
KIF18A participates in Amplification of signal from the kinetochoresPathwayReactome R-HSA-141424Inferred only
KIF18A participates in Cell CyclePathwayReactome R-HSA-1640170Inferred only
KIF18A participates in Cell Cycle CheckpointsPathwayReactome R-HSA-69620Inferred only
KIF18A participates in Cell Cycle, MitoticPathwayReactome R-HSA-69278Inferred only
KIF18A participates in COPI-dependent Golgi-to-ER retrograde trafficPathwayReactome R-HSA-6811434Inferred only
KIF18A participates in EML4 and NUDC in mitotic spindle formationPathwayReactome R-HSA-9648025Inferred only

Show the remaining 28

KIF18A participates in Factors involved in megakaryocyte development and platelet productionPathwayReactome R-HSA-983231Inferred only
KIF18A participates in Golgi-to-ER retrograde transportPathwayReactome R-HSA-8856688Inferred only
KIF18A participates in HemostasisPathwayReactome R-HSA-109582Inferred only
KIF18A participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
KIF18A participates in Immunoglobulin maturationPathwayReactome R-HSA-9938026Inferred only
KIF18A participates in Intra-Golgi and retrograde Golgi-to-ER trafficPathwayReactome R-HSA-6811442Inferred only
KIF18A participates in KinesinsPathwayReactome R-HSA-983189Inferred only
KIF18A participates in M PhasePathwayReactome R-HSA-68886Inferred only
KIF18A participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
KIF18A participates in MHC class II antigen presentationPathwayReactome R-HSA-2132295Inferred only
KIF18A participates in Mitotic AnaphasePathwayReactome R-HSA-68882Inferred only
KIF18A participates in Mitotic Metaphase and AnaphasePathwayReactome R-HSA-2555396Inferred only
KIF18A participates in Mitotic PrometaphasePathwayReactome R-HSA-68877Inferred only
KIF18A participates in Mitotic Spindle CheckpointPathwayReactome R-HSA-69618Inferred only
KIF18A participates in Processing of antigen in germinal center B cellsPathwayReactome R-HSA-9979719Inferred only
KIF18A participates in Resolution of Sister Chromatid CohesionPathwayReactome R-HSA-2500257Inferred only
KIF18A participates in RHO GTPase EffectorsPathwayReactome R-HSA-195258Inferred only
KIF18A participates in RHO GTPases Activate ForminsPathwayReactome R-HSA-5663220Inferred only
KIF18A participates in Separation of Sister ChromatidsPathwayReactome R-HSA-2467813Inferred only
KIF18A participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
KIF18A participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
KIF18A participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only
KIF18A participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
DECR1 decreases the expression of KIF18AProteinHetionet hetionet:regulates:1666-81930Inferred only
ETV1 decreases the expression of KIF18AProteinHetionet hetionet:regulates:2115-81930Inferred only
FBXO7 decreases the expression of KIF18AProteinHetionet hetionet:regulates:25793-81930Inferred only
LIG1 decreases the expression of KIF18AProteinHetionet hetionet:regulates:3978-81930Inferred only
UVRAG decreases the expression of KIF18AProteinHetionet hetionet:regulates:7405-81930Inferred only

Other names

2 names

Resolves to: KIF18A

Also called: Marrow stromal KIF18AMS-KIF18A

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