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Proteins/UNIPROT:P07910
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing..
Function from UniProtKB (P07910), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
91 statements
91 statements · 4 reference databases · Subject: HNRNPC · Sources: gene ontology, Hetionet, Reactome, WikiPathways
3 names
Resolves to: HNRNPC