Proteins/UNIPROT:Q96QV6

H2AC1

ProteinUNIPROT:Q96QV6

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Function from UniProtKB (Q96QV6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

32 statements

32 statements · 2 reference databases · Subject: H2AC1 · Sources: Hetionet, Reactome

Order

ACTB covaries with H2AC1ProteinHetionet hetionet:covaries:221613-60Inferred only
H2AC1 covaries with ANKRD28ProteinHetionet hetionet:covaries:221613-23243Inferred only
H2AC1 covaries with CNOT8ProteinHetionet hetionet:covaries:221613-9337Inferred only
H2AC1 covaries with DPYSL3ProteinHetionet hetionet:covaries:1809-221613Inferred only
H2AC1 covaries with HNRNPH3ProteinHetionet hetionet:covaries:221613-3189Inferred only
H2AC1 covaries with ITFG2ProteinHetionet hetionet:covaries:221613-55846Inferred only
JAZF1 covaries with H2AC1ProteinHetionet hetionet:covaries:221613-221895Inferred only
H2AC1 covaries with SPON1ProteinHetionet hetionet:covaries:10418-221613Inferred only
H2AC1 covaries with TMEM59ProteinHetionet hetionet:covaries:221613-9528Inferred only
EIF4A3 interacts with H2AC1ProteinHetionet hetionet:interacts:221613-9775Inferred only
MAGOH interacts with H2AC1ProteinHetionet hetionet:interacts:221613-4116Inferred only
PCLAF interacts with H2AC1ProteinHetionet hetionet:interacts:221613-9768Inferred only

Show the remaining 20

UBC interacts with H2AC1ProteinHetionet hetionet:interacts:221613-7316Inferred only
H2AC1 participates in Chromatin modifying enzymesPathwayReactome R-HSA-3247509Inferred only
H2AC1 participates in Chromatin organizationPathwayReactome R-HSA-4839726Inferred only
H2AC1 participates in Dengue Virus InfectionPathwayReactome R-HSA-9839923Inferred only
H2AC1 participates in Dengue Virus-Host InteractionsPathwayReactome R-HSA-9918481Inferred only
H2AC1 participates in DeubiquitinationPathwayReactome R-HSA-5688426Inferred only
H2AC1 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
H2AC1 participates in HATs acetylate histonesPathwayReactome R-HSA-3214847Inferred only
H2AC1 participates in HCMV Early EventsPathwayReactome R-HSA-9609690Inferred only
H2AC1 participates in HCMV InfectionPathwayReactome R-HSA-9609646Inferred only
H2AC1 participates in HCMV Late EventsPathwayReactome R-HSA-9610379Inferred only
H2AC1 participates in HDACs deacetylate histonesPathwayReactome R-HSA-3214815Inferred only
H2AC1 participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
H2AC1 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
H2AC1 participates in Metalloprotease DUBsPathwayReactome R-HSA-5689901Inferred only
H2AC1 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
H2AC1 participates in RMTs methylate histone argininesPathwayReactome R-HSA-3214858Inferred only
H2AC1 participates in Ub-specific processing proteasesPathwayReactome R-HSA-5689880Inferred only
H2AC1 participates in UCH proteinasesPathwayReactome R-HSA-5689603Inferred only
H2AC1 participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only

Other names

4 names

Resolves to: H2AC1

Also called: H2A-clustered histone 1H2AFRHIST1H2AAHistone H2A/r

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