Proteins/UNIPROT:P40197

GP5

ProteinUNIPROT:P40197

The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.

Function from UniProtKB (P40197), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

30 statements

30 statements · 4 reference databases · Subject: GP5 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

GP5 covaries with ARID3BProteinHetionet hetionet:covaries:10620-2814Inferred only
GP5 covaries with C3AR1ProteinHetionet hetionet:covaries:2814-719Inferred only
CIZ1 covaries with GP5ProteinHetionet hetionet:covaries:25792-2814Inferred only
HAVCR2 covaries with GP5ProteinHetionet hetionet:covaries:2814-84868Inferred only
GP5 covaries with LCTLProteinHetionet hetionet:covaries:197021-2814Inferred only
NTMT1 covaries with GP5ProteinHetionet hetionet:covaries:2814-28989Inferred only
PCDHB6 covaries with GP5ProteinHetionet hetionet:covaries:2814-56130Inferred only
SPZ1 covaries with GP5ProteinHetionet hetionet:covaries:2814-84654Inferred only
GP5 covaries with TAPBPLProteinHetionet hetionet:covaries:2814-55080Inferred only
GP5 covaries with TOR1AIP1ProteinHetionet hetionet:covaries:26092-2814Inferred only
GP1BA interacts with GP5ProteinHetionet hetionet:interacts:2811-2814Inferred only
GP5 participates in 22q11 2 copy number variation syndromePathwayWikiPathways WP4657Inferred only

Show the remaining 18

GP5 participates in Amplification and propagation of coagulation cascadePathwayReactome R-HSA-9769743Inferred only
GP5 participates in Coagulation pathwayPathwayReactome R-HSA-9769740Inferred only
GP5 participates in Defective binding of VWF variant to GPIb:IX:VPathwayReactome R-HSA-9846298Inferred only
GP5 participates in Defective F9 activationPathwayReactome R-HSA-9673221Inferred only
GP5 participates in Defective factor IX causes hemophilia BPathwayReactome R-HSA-9668250Inferred only
GP5 participates in Defects of Coagulation cascadePathwayReactome R-HSA-9769726Inferred only
GP5 participates in Defects of platelet adhesion to exposed collagenPathwayReactome R-HSA-9823587Inferred only
GP5 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
GP5 participates in Diseases of hemostasisPathwayReactome R-HSA-9671793Inferred only
GP5 participates in Enhanced binding of GP1BA variant to VWF multimer:collagenPathwayReactome R-HSA-9845620Inferred only
GP5 participates in FXIIa, PKa-dependent activation of coagulation pathwayPathwayReactome R-HSA-9935598Inferred only
GP5 participates in GP1b-IX-V activation signallingPathwayReactome R-HSA-430116Inferred only
GP5 participates in HemostasisPathwayReactome R-HSA-109582Inferred only
GP5 participates in Platelet activation, signaling and aggregationPathwayReactome R-HSA-76002Inferred only
GP5 participates in Platelet Adhesion to exposed collagenPathwayReactome R-HSA-75892Inferred only
GP5 participates in Platelet Aggregation (Plug Formation)PathwayReactome R-HSA-76009Inferred only
GP5 participates in Regulation of clotting cascadePathwayReactome R-HSA-9769739Inferred only
GP5 regulates positive regulation of platelet activationBiological processgene ontology P40197|GO:0010572Inferred only

Other names

3 names

Resolves to: GP5

Also called: CD antigen CD42dGlycoprotein 5GPV

← Every protein Find it in the graph →