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Proteins/UNIPROT:Q6XZF7
Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity)..
Function from UniProtKB (Q6XZF7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
44 statements
44 statements · 4 reference databases · Subject: DNMBP · Sources: gene ontology, Hetionet, Reactome, WikiPathways
5 names
Resolves to: DNMBP