Proteins/UNIPROT:Q9NVR5

DNAAF2

ProteinUNIPROT:Q9NVR5

Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment..

Function from UniProtKB (Q9NVR5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

primary ciliary dyskinesia has a germline basis in DNAAF2DiseaseGenCC HGNC:20188|MONDO:0016575Inferred only
primary ciliary dyskinesia 10 has a germline basis in DNAAF2DiseaseGenCC HGNC:20188|MONDO:0012918Inferred only

Statements

11 statements

11 statements · 2 reference databases · Subject: DNAAF2 · Sources: Hetionet, WikiPathways

Order

ANKRD24 covaries with DNAAF2ProteinHetionet hetionet:covaries:170961-55172Inferred only
DENND1C covaries with DNAAF2ProteinHetionet hetionet:covaries:55172-79958Inferred only
PDE4A covaries with DNAAF2ProteinHetionet hetionet:covaries:5141-55172Inferred only
APP interacts with DNAAF2ProteinHetionet hetionet:interacts:351-55172Inferred only
UBC interacts with DNAAF2ProteinHetionet hetionet:interacts:55172-7316Inferred only
DNAAF2 participates in CiliopathiesPathwayWikiPathways WP4803Inferred only
ANXA7 decreases the expression of DNAAF2ProteinHetionet hetionet:regulates:310-55172Inferred only
MTF2 decreases the expression of DNAAF2ProteinHetionet hetionet:regulates:22823-55172Inferred only
POLE2 decreases the expression of DNAAF2ProteinHetionet hetionet:regulates:5427-55172Inferred only
RRM1 decreases the expression of DNAAF2ProteinHetionet hetionet:regulates:6240-55172Inferred only
TPI1 decreases the expression of DNAAF2ProteinHetionet hetionet:regulates:7167-55172Inferred only

Other names

5 names

Resolves to: DNAAF2

Also called: C14orf104Dynein assembly factor 2, axonemalkintounKTUProtein kintoun

← Every protein Find it in the graph →