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Proteins/UNIPROT:Q13561
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. In the dynactin soulder domain, binds the ACTR1A filament and acts as a molecular ruler to determine the length (By similarity). Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity)..
Function from UniProtKB (Q13561), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
72 statements
72 statements · 3 reference databases · Subject: DCTN2 · Sources: Hetionet, Reactome, WikiPathways
5 names
Resolves to: DCTN2