Proteins/UNIPROT:O75534

CSDE1

ProteinUNIPROT:O75534

RNA-binding protein involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Required for efficient formation of stress granules..

(Microbial infection) Required for internal initiation of translation of human rhinovirus RNA..

Function from UniProtKB (O75534), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

complex neurodevelopmental disorder has a germline basis in CSDE1DiseaseGenCC HGNC:29905|MONDO:0100038Inferred only

Statements

26 statements

26 statements · 3 reference databases · Subject: CSDE1 · Sources: gene ontology, Hetionet, WikiPathways

Order

RBM17 covaries with CSDE1ProteinHetionet hetionet:covaries:7812-84991Inferred only
CSDE1 interacts with COPS5ProteinHetionet hetionet:interacts:10987-7812Inferred only
CSDE1 interacts with CUL3ProteinHetionet hetionet:interacts:7812-8452Inferred only
HNRNPD interacts with CSDE1ProteinHetionet hetionet:interacts:3184-7812Inferred only
NCK1 interacts with CSDE1ProteinHetionet hetionet:interacts:4690-7812Inferred only
CSDE1 interacts with PABPC1ProteinHetionet hetionet:interacts:26986-7812Inferred only
CSDE1 interacts with PCLAFProteinHetionet hetionet:interacts:7812-9768Inferred only
CSDE1 interacts with PCSK7ProteinHetionet hetionet:interacts:7812-9159Inferred only
PIK3R1 interacts with CSDE1ProteinHetionet hetionet:interacts:5295-7812Inferred only
PRKAB1 interacts with CSDE1ProteinHetionet hetionet:interacts:5564-7812Inferred only
CSDE1 interacts with SIRT7ProteinHetionet hetionet:interacts:51547-7812Inferred only
STT3A interacts with CSDE1ProteinHetionet hetionet:interacts:3703-7812Inferred only

Show the remaining 14

CSDE1 interacts with SYNCRIPProteinHetionet hetionet:interacts:10492-7812Inferred only
TRAF6 interacts with CSDE1ProteinHetionet hetionet:interacts:7189-7812Inferred only
UBC interacts with CSDE1ProteinHetionet hetionet:interacts:7316-7812Inferred only
UBE2I interacts with CSDE1ProteinHetionet hetionet:interacts:7329-7812Inferred only
CSDE1 interacts with WNK1ProteinHetionet hetionet:interacts:65125-7812Inferred only
CSDE1 participates in miR targeted genes in lymphocytesPathwayWikiPathways WP2004Inferred only
CSDE1 participates in miR targeted genes in muscle cellPathwayWikiPathways WP2005Inferred only
CSDE1 participates in miR targeted genes in squamous cellPathwayWikiPathways WP2006Inferred only
CSDE1 regulates negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decayBiological processgene ontology O75534|GO:1900152Inferred only
CSDE1 regulates positive regulation of cytoplasmic translationBiological processgene ontology O75534|GO:2000767Inferred only
CSDE1 regulates positive regulation of translationBiological processgene ontology O75534|GO:0045727Inferred only
CSDE1 regulates regulation of translational initiationBiological processgene ontology O75534|GO:0006446Inferred only
EFCAB14 decreases the expression of CSDE1ProteinHetionet hetionet:regulates:9813-7812Inferred only
PSMD10 decreases the expression of CSDE1ProteinHetionet hetionet:regulates:5716-7812Inferred only

Other names

6 names

Resolves to: CSDE1

Also called: D1S155EKIAA0885N-ras upstream gene proteinNRUProtein UNRUNR

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